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Cutaneous and Mucocutaneous Leishmaniasis
Leishmaniasis is a chronic disease caused by flagellate protozoa of the genus Leishmania. It is a global disease, but most cases are seen in South America, the Mediterranean, and some areas of Asia and Africa. The 3 main types of leishmaniasis are cutaneous (the most common), mucocutaneous, and visceral (the most severe). Visceral leishmaniasis is also
P A Cerro +4 more
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Biomarkers of Cutaneous Leishmaniasis [PDF]
Cutaneous leishmaniasis (CL) is an immune-mediated skin pathology caused mainly by Leishmania (L.) major, Leishmania tropica, Leishmania braziliensis, L. mexicana, and L. amazonensis. The burden of CL in terms of morbidity and social stigmas are concentrated on certain developing countries in Asia, Africa, and South America. People with asymptomatic CL
Bahrami +3 more
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Complete Resolution of Cutaneous Leishmaniasis With a Novel Topical Combination Therapy: A Case Series. [PDF]
ABSTRACT Cutaneous leishmaniasis (CL) remains a therapeutic challenge in endemic regions, with 600,000–1 million new cases annually facing limited treatment options. We present a case series evaluating an innovative topical combination therapy for acute‐phase CL in Shiraz, Iran.
Haghshenas H +3 more
europepmc +2 more sources
Cutaneous Leishmaniasis: A 2022 Updated Narrative Review into Diagnosis and Management Developments
This review is an update of an earlier narrative review published in 2015 on developments in the clinical management of cutaneous leishmaniasis (CL) including diagnosis, treatment, prevention and control measurements.
H. D. de Vries, Henk Schallig
semanticscholar +1 more source
Leishmaniasis is a neglected tropical disease that affects 12 million people worldwide. The disease has high morbidity and mortality rates and is prevalent in over 80 countries, leaving more than 300 million people at risk of infection.
Greta Volpedo +5 more
semanticscholar +1 more source
Therapeutic advances in the topical treatment of cutaneous leishmaniasis: A review
Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported worldwide specially in developing and underdeveloped countries. There are 2 major types of cutaneous leishmaniasis based on the causating species found in different ...
M. Azim +4 more
semanticscholar +1 more source
Host-Directed Therapies for Cutaneous Leishmaniasis
Cutaneous leishmaniasis exhibits a wide spectrum of clinical presentations from self-resolving infections to severe chronic disease. Anti-parasitic drugs are often ineffective in the most severe forms of the disease, and in some cases the magnitude of ...
F. Novais, C. Amorim, P. Scott
semanticscholar +1 more source
The Sociodemographic Risk Factors Associated With Cutaneous Leishmaniasis of the Hazara Community of Quetta, Balochistan, Pakistan: A Cross-Sectional Study. [PDF]
ABSTRACT Background/Aim Cutaneous leishmaniasis (CL) is a protozoan disease transmitted by sandflies, causing skin lesions and scars. In Pakistan, the Hazara community in Balochistan is significantly affected, with over 400,000 cases reported in 2016.
Ali Z +7 more
europepmc +2 more sources
Leishmania tropica and Leishmania major are both the main cause of anthroponotic (ACL) and zoonotic cutaneous leishmaniasis (ZCL), respectively, in the Old World.
M. A. Ghatee, W. Taylor, M. Karamian
semanticscholar +1 more source
Systemic Treatments of Leishmaniasis: A Narrative Review [PDF]
Cutaneous leishmaniasis is a prevalent parasitic infection in humans. According to the reports published in several localities across the world, leishmaniasis is an endemic disease in certain regions in Iran.
Ahmad Reza Taheri +2 more
doaj +1 more source

