Results 21 to 30 of about 27,893 (216)

Two Cases of Chronic and Drug-Resistant Cutaneous Leishmaniasis as an Initial Presentation of the Underlying Lymphoproliferative Disorder

مجله دانشکده پزشکی اصفهان, 2020
Background: Cutaneous leishmaniasis is an infectious disease caused by the protozoa of Leishmania genus, which cause serious public health issues in endemic regions across 80 countries.
Reza Mortezaei, Reihaneh Aryan, Saman Afkhami-Ardakani, Vahid Mashayekhi-Goyonlo   +3 more
doaj   +1 more source

Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study

Nepal Journal of Dermatology, Venereology & Leprology, 2023
Introduction: Cutaneous leishmaniasis is a tropical disease transmitted by the bite of an intracellular parasite infected sandfly. Visceral leishmaniasis is common in Nepal. However, cutaneous leishmaniasis remains rare with only limited number of cases
Sushmita Pradhan, Shristee Shrestha, Damber Khadka, Niraj Parajuli, Suwash Baral, Daisuke Tsuruta   +5 more
doaj   +3 more sources

Salvage therapy with Sodium chlorosum (formerly DAC N-055) for cases of refractory lupoid cutaneous leishmaniasis: results from a compassionate use study with 0.09% Sodium chlorosum in amphiphilic basic cream

BMC Infectious Diseases, 2019
Background Lupoid cutaneous leishmaniasis (LCL) is known as a rare but serious complication of anthroponotic cutaneous leishmaniasis (ACL) resistant to conventional treatments.
Sara Molkara, Elaheh Poursoltani, Kurt-Wilhelm Stahl, Masoud Maleki, Ali Khamesipour, Christian Bogdan, Maryam Salehi, Vahid Mashayekhi Goyonlo   +7 more
doaj   +1 more source

The Association of Serum Lipid Profiles and Dietary Intakes of Vitamin E and Fiber with Psoriasis Severity

Caspian Journal of Internal Medicine, 2021
Background: Dyslipidemia has been reportedly associated with an increased risk of atherosclerosis among psoriatic patients. Dietary intake can be a key factor in the pathophysiology of psoriasis. Herein, we assessed serum lipid profile and dietary intake
Mohammad Javad Yazdanpanah, Sadegh Vahabi-Amlashi, Mohsen Nematy, Neda Shaelaei, Seyed Amir Reza Mohajeri, Zahra Tafazzoli   +5 more
doaj  

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Symmetrical Cutaneous Leishmaniasis

Acta Dermato-Venereologica, 2005
Sir, Cutaneous leishmaniasis (CL) is a protozoan disease present in Old and New Worlds (1, 2). It is endemic in the Mediterranian basin, particularly in the rural areas of Sicily where almost 60% of Italian cases occur. The disease is caused by parasites of the genus Leishmania infantum, carried by specific species of sandflies as Phlebotomus ...
GUARNERI, Claudio, GUARNERI, Fabrizio Nicola Giuseppe   +1 more
openaire   +2 more sources

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, EarlyView.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Clinical and epidemiological aspects of American cutaneous leishmaniasis with genital involvement, [PDF]

Anais Brasileiros de Dermatologia, 2020
Genital lesions are an unusual presentation of American cutaneous leishmaniasis. Conditions such as disseminated cutaneous leishmaniasis and HIV infection may be associated with genital involvement.
Marcelo Rosandiski Lyra, Alan Bittencourt da Silva, Cláudia Maria Valete-Rosalino, Maria Inês Fernandes Pimentel   +3 more
doaj   +1 more source

Plasma levels of interlukin-4 and Interferon- in patients with chronic or healed cutaneous leishmaniasis [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s):In this study, the serum level of interferon-γ (IFN- γ) and interlukin-4 (IL-4) was evaluated as a marker of Th1 and Th2 immune response that influence the clinical course of cutaneous leishmaniasis[r1] .
Ahmad Reza Taheri, Vahid Mashayekhi Goyonlo, Yalda Nahidi, Nasrin Moheghi, Jalil Tavakkol Afshari   +4 more
doaj  

Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis

Dermatology Research and Practice, 2011
The purpose of this study was to investigate comparison between oral zinc sulfate and meglumine antimoniate in the treatment of cutaneous leishmaniasis (CL). So 100 patients with CL were included and randomly divided into two groups.
Mohamad Javad Yazdanpanah, Mahnaz Banihashemi, Fakhrozaman Pezeshkpoor, Mohammad Khajedaluee, Sororozaman Famili, Iman Tavakoli Rodi, Hadis Yousefzadeh   +6 more
doaj   +1 more source