Results 61 to 70 of about 53,720 (250)

Reflectance confocal microscopy for the diagnosis of skin infections and infestations [PDF]

, 2020
Reflectance confocal microscopy (RCM) is a noninvasive real-time imaging technique that has been widely used for the diagnosis of skin cancer. More recently, it has been reported as a useful tool for the diagnosis and management of several inflammatory ...
Arzberger, Edith, Bastos, Pedro Mendes, Ferreira, João, Leal-Filipe, Paulo, Oliveira, André Laureano, Pimenta, Rita, Soares-de-Almeida, Luís   +6 more
core  

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]

, 1994
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM, Reiner, SL, Stowring, L, Wang, ZE, Zheng, S   +4 more
core   +1 more source

American Cutaneous Leishmaniasis

Archives of Pathology & Laboratory Medicine, 2002
Abstract We present 3 cases of American cutaneous leishmaniasis occurring in soldiers of a unit of US Army Rangers who parachuted into the jungles of Panama. Shortly after returning to the United States, these 3 soldiers each developed a crusted, indurated papule, which slowly enlarged during the following 6 weeks.
M A J Michael, Royer, C O L Mark, Crowe
openaire   +2 more sources

Defensive medicine in dermatological practice – Dermatopathology as a mirror of structural challenges

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller, Torsten Hansen, Claus Renzelmann   +2 more
wiley   +1 more source

Differential effects of antigens from L. braziliensis isolates from disseminated and cutaneous leishmaniasis on in vitro cytokine production

BMC Infectious Diseases, 2006
Background Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from cutaneous leishmaniasis.
Guimarães Luiz, Ho John L, de Jesus Amélia, Giudice Angela, Schriefer Albert, Almeida Roque P, Machado Paulo RL, Leopoldo Paulo TG, Bacellar Olívia, Carvalho Edgar M   +9 more
doaj   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, EarlyView.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Kidney involvement in leishmaniasis—a review

Brazilian Journal of Infectious Diseases, 2014
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp.
Geraldo Bezerra da Silva Junior, Elvino José Guardão Barros, Elizabeth De Francesco Daher   +2 more
doaj   +1 more source

'We do not rush to the hospital for ordinary wounds (suḷu tuvāla)': A qualitative study on the early clinical manifestations of cutaneous leishmaniasis and associated health behaviours in rural Sri Lanka.

PLoS Neglected Tropical Diseases, 2023
BackgroundKnowledge of early clinical manifestations, people's perceptions and behaviours is crucial in preventing and controlling neglected tropical diseases (NTDs).
Sonali Dinushika Gunasekara, Nuwan Darshana Wickramasinghe, Suneth Buddhika Agampodi, Manoj Sanjeewa Fernando, Kosala Gayan Weerakoon, Chandani Liyanage, Lisa Dikomitis, Thilini Chanchala Agampodi   +7 more
doaj   +1 more source

Declining Visceral Leishmaniasis in Malta [PDF]

, 2008
Aims: To study visceral leishmaniasis (VL) trends in Malta. Methods: Analysis of epidemiological and clinical trends, a veterinary questionnaire and questioning a canine laboratory testing facility.
Grech, Victor E., Vella, Cecil
core  

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source