Results 71 to 80 of about 26,133 (216)
Synthetic Biology in Leishmaniasis: Design,simulation and validation of constructed Genetic circuit [PDF]
arXiv, 2013 Building circuits and studying their behavior in cells is a major goal of systems and synthetic biology. Synthetic biology enables the precise control of cellular states for systems studies, the discovery of novel parts, control strategies, and interactions for the design of robust synthetic systems. To the best of our knowledge,there are no literature
arxiv
The role of disease cycles in the endemicity of infectious diseases [PDF]
arXiv, 2017 Vector-borne diseases with reservoir cycles are complex to understand because new infections come from contacts of the vector with humans and different reservoirs. In this scenario, the basic reproductive number $\mathcal{R}^h_0$ of the system where the reservoirs are not included could turn out to be less than one, yet, an endemic equilibrium be ...
arxiv
In Silico Prediction and Validation of LmGt Inhibitors Using QSAR and Molecular Docking Approaches [PDF]
Proceedings of the 2025 IEEE International Conference on
Innovation in Computing and Engineering (ICE), Greater Noida, India, pp. 1 to
5, 2025Leishmaniasis caused by Leishmania mexicana relies on Leishmania mexicana gluscose transporter (LmGT) receptors, which play an important role in glucose and ribose uptake at different stages of parasite's life cycle. Previous efforts to identify LmGT inhibitors have been primarily based on in vitro screening.
arxiv +1 more source
Rethinking Histology Slide Digitization Workflows for Low-Resource Settings [PDF]
arXivHistology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical workflows). However, the cumulative costs of digital multi-slide high-speed brightfield scanners, cloud/on-premises storage,
arxiv
Skin Health and DiseaseBackground Neglected tropical diseases, affecting over a billion people, include leishmaniasis, a protozoan parasite found in over 20 species. It is classified into three types: visceral, cutaneous, and muco‐cutaneous leishmaniasis, with cutaneous ...
Abdilahi Ibrahim Muse +2 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2004 The wide variety of Leishmania species responsible for human American cutaneous leishmaniasis combined with the immune mechanisms of the host results in a large spectrum of clinical, histopathological, and immunopathological manifestations. At the middle
Fernando T Silveira +2 more
doaj +1 more source
Learning a Generative Model of Cancer Metastasis [PDF]
arXiv, 2019 We introduce a Unified Disentanglement Network (UFDN) trained on The Cancer Genome Atlas (TCGA). We demonstrate that the UFDN learns a biologically relevant latent space of gene expression data by applying our network to two classification tasks of cancer status and cancer type.
arxiv
PLoS Neglected Tropical DiseasesBackgroundCutaneous leishmaniasis is a widespread parasitic infection in Ethiopia. Few studies have been conducted on knowledge, attitudes, and prevention practice related to cutaneous leishmaniasis, and the existing studies have been mainly without ...
Abebe Kassa Geto +9 more
doaj +1 more source
Detecting cutaneous basal cell carcinomas in ultra-high resolution and weakly labelled histopathological images [PDF]
arXiv, 2019 Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions, i.e. computer-assisted diagnoses is actively researched to improve safety, quality and efficiency.
arxiv
Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. [PDF]
, 1988 Phillip Scott +4 more
openalex +1 more source