Results 101 to 110 of about 757,323 (338)
p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis [PDF]
, 2013 The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Graf, M +47 more
core +1 more source
Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center
JEADV Clinical Practice, EarlyView.ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres +4 more
wiley +1 more source
Acta Dermato-Venereologica, 2013 Clinical management of primary cutaneous melanomas is based on histopathological staging of the tumour. The aim of this study was to investigate, in a non-selected population in clinical practice, the agreement rate between general pathologists and ...
H. Eriksson +8 more
semanticscholar +1 more source
Current Problems in Dermatology, 1993 Abstract Malignant melanoma is the leading cause of death as a result of skin disease in the United States. The incidence of melanoma has increased exponentially during the last two decades, and the disease is now the eighth most common cause of cancer in the United States, with an estimated annual incidence of approximately 13 per 100,000.
Stephen J. Hoffman +4 more
openaire +3 more sources
Clear Cell Sarcoma of the Knee. A Report of Two Rare Cases [PDF]
Malaysian Orthopaedic Journal, 2011 Clear cell sarcoma of soft tissue is a rare type of soft tissue sarcoma. It is derived from melanoblast-like cells located within subcutaneous tissue, tendon and aponeuroses.
ZA Ibrahim, KL Pan, PS Shanmugam
doaj
Malignant Melanoma with Concurrent BRAF E586K and NRAS Q81K Mutations
Case Reports in Oncology, 2014 Cutaneous melanoma is an aggressive malignant tumor of melanocytes which accounts for 80% of skin cancer-related deaths. A number of driver mutations have been identified in melanoma, with the mutually exclusive BRAF V600E and NRAS Q61A mutations ...
Rodney Shackelford +5 more
doaj +1 more source
Chemotherapy in the Management of Advanced Cutaneous Malignant Melanoma
Clinical Dermatology, 2013 The recent past has witnessed unprecedented clinical progress in the treatment of advanced malignant melanoma through targeting of mutant BRAF in approximately 50 percent of patients and immune check point blockade in all patients.
J. Luke, G. Schwartz
semanticscholar +1 more source
JEADV Clinical Practice, EarlyView.Vitiligo was associated with directionally lower odds of melanoma and non‐melanoma skin cancer in this systematic review and meta‐analysis of 14 studies. A statistically significant inverse association was observed for squamous cell carcinoma. Phototherapy exposure showed higher, but non‐significant, point estimates for melanoma and non‐melanoma skin ...
Simonetta I. Gaumond +8 more
wiley +1 more source
Artificial Intelligence in Dermatology: Current Applications and Future Directions
JEADV Clinical Practice, EarlyView.This scoping review of 56 studies maps AI applications in dermatology. Image‐based classification for skin cancer detection dominates (48%), followed by clinical decision support (21%), teledermatology triage (11%), and predictive analytics (11%). While deep learning algorithms demonstrate diagnostic performance comparable to clinicians in controlled ...
Sofía Pérez‐Lalinde +1 more
wiley +1 more source
Molecular and cellular pathogenesis of melanoma initiation and progression [PDF]
, 2013 Melanoma is a malignant tumour of melanocytes, which can spread to other organs of the body resulting in severe and/or lethal malignancies. Melanocytes are pigment producing cells found in deep layer of the epidermis and are originated from melanocytes ...
Regad, T
core +1 more source