Results 111 to 120 of about 68,932 (348)

Cutaneous Squamous Cell Carcinoma (SCC) and the DNA Damage Response:pATM Expression Patterns in Pre-Malignant and Malignant Keratinocyte Skin Lesions

, 2011
Recent evidence suggests that an initial barrier to the emergence of tumours is a DNA damage response that evokes a counter-response which arrests the growth of, or eliminates, damaged cells.
Ismail, F, Leigh Irene, Ferina Ismail, Ikram, Mohamed, Ismail Ferina, Purdie Karin, Ismail, Ferina, Purdie, K, Mohamed Ikram, Storey, A, Leigh, Irene, Storey, Alan, Ikram Mohamed, Storey Alan, Leigh, I, Purdie, Karin, Catherine Harwood, Harwood, Catherine, Karin Purdie, Harwood Catherine, Harwood, C, Alan Storey, Ikram, M, Irene Leigh   +23 more
core   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Primary cutaneous malignant melanoma of the breast

Journal of the Korean Surgical Society, 2012
Cutaneous malignant melanoma of the breast can be divided into two categories: primary and metastatic lesions. Cutaneous malignant melanoma of the breast is a rare tumor, accounting for less than 5% of all malignant melanomas.
Seon Kwang Kim, Young Wook Kim, H. Youn, Ho-Sung Park, S. Jung   +4 more
semanticscholar   +1 more source

A Large Pigmented Lesion on the Abdomen of a Woman

JEADV Clinical Practice, EarlyView.
Ángel Fernández‐Camporro, Julián José Ahijado‐González, Eva Miranda‐Martínez   +2 more
wiley   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

Rheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura, Yasuhiro Katsumata, Yuko Okamoto, Masayoshi Harigai   +3 more
wiley   +1 more source

Classification of the Clinical Images for Benign and Malignant Cutaneous Tumors Using a Deep Learning Algorithm.

Journal of Investigative Dermatology, 2018
We tested the use of a deep learning algorithm to classify the clinical images of 12 skin diseases-basal cell carcinoma, squamous cell carcinoma, intraepithelial carcinoma, actinic keratosis, seborrheic keratosis, malignant melanoma, melanocytic nevus ...
S. Han, M. Kim, Woohyung Lim, Gyeong-Hun Park, I. Park, S. Chang   +5 more
semanticscholar   +1 more source

Molecular genetics and mechanisms of pigmentation and melanoma [PDF]

, 2010
Ever since man domesticated the first wild animals several thousand years ago, many species have been living in close relationship with humans, being objects for our requests and wishes about any kind of phenotypic traits.
Sundström, Elisabeth
core  

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Primary retroperitoneal malignant melanoma

The Pan African Medical Journal, 2012
Malignant melanoma is a tumour arising from the melancytes which are derived from the neural crest, it migrate during the embryological development and may be found in the non cutoneons site.
Aziz Zentar, Rabie Makhmari, Hicham Elkaoui, Mohammed Bouchentouf, Hicham Lahnini, Said Belhamid, Ahmed Bounaim, Abdelmounaim Aitali, Khalid Sair   +8 more
doaj   +1 more source

Primary bilateral malignant melanoma of the lower limbs

Dermatology Reports, 2011
Malignant melanoma is the eighth most common cancer in European women. Its incidence is increasing rapidly and it has been demonstrated that this is related to sun exposure.
Serena Lembo, Matteo Megna, Paolo Maddalena, Ambra Monfrecola, Anna Balato, Antonello Baldo   +5 more
doaj   +1 more source