Results 241 to 250 of about 757,323 (338)

The role of wide local excision of a primary lesion in cutaneous malignant melanoma: a retrospective analysis of its usefulness in local and general control of disease. [PDF]

Melanoma Res
Nacchiero E, Giotta M, Robusto F, Metta ME, Ronghi V, Elia R, Trerotoli P, Maruccia M, Giudice G.   +8 more
europepmc   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

The FOXQ1/SSBP2 Regulatory Axis Drives Malignant Progression of Melanoma

Molecular Carcinogenesis, Volume 65, Issue 11, Page 1459-1477, November 2026.
ABSTRACT Melanoma is a highly aggressive skin cancer with poor prognosis, often linked to excessive UV exposure. Despite advancements in immunotherapy and targeted treatments, melanoma's invasiveness and metastatic potential remain significant challenges.
Xiaoyu Zhang, Yu Hou, Jiahui Liu, Yuehua Han, Jiangang Feng   +4 more
wiley   +1 more source

The role of CCND1 alterations during the progression of cutaneous malignant melanoma

Tumor Biology, 2012
L. Vízkeleti, Szilvia Ecsedi, Z. Rákosy, Adrienn Orosz, Viktória Lázár, G. Emri, V. Koroknai, T. Kiss, R. Ádány, M. Balázs   +9 more
semanticscholar   +1 more source

Diabetes and melanoma: Impact on prognosis and healthcare costs

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Alessandra Buja, Marcello Di Pumpo, Chiara Trevisiol, Claudio Palmeri, Marina Coppola, Giorgia Zorzetto, Paolo Del Fiore, Stefano Guzzinati, Laura Memo, Giulia Grotto, Carlo Riccardo Rossi, Pierfranco Conte, Manuel Zorzi, Simone Mocellin   +13 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

The Journal of Pathology, Volume 270, Issue 3, Page 380-395, November 2026.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti, Martina Brigida Romanello, Luca Agnelli, Matteo Orlandi, Luca Bertoli, Sara Picinoli, Irene Pezzali, Giulio Eugenio Mandelli, Daniela Medicina, Giovanni Ribaudo, Adele Busico, Elena Conca, Vilma Pellegrini, Piera Balzarini, Daniele Gallucci, Anna Di Matteo, Davide Lombardi, Claudia Ghigna, Giancarlo Pruneri, Alessandra Gianoncelli, Marzia Rossato, William Vermi   +21 more
wiley   +1 more source

Anaplastic cutaneous plasmacytoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva, Júlia Kaori Hayashi, Danielle Cavalcanti Carvalho de Diniz, Maria Lucia Gomes Lourenço, Luiz Henrique Araujo de Machado   +4 more
wiley   +1 more source

Pancarpal arthrodesis with medial plate fixation following amputation of metacarpal II in a dog with extensive digital squamous cell carcinoma

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 10‐year‐old, male neutered, Scottish Terrier was referred for progressive right forelimb lameness attributed to a firm spherical mass in the location of a previous digit I amputation, performed 13‐months prior to presentation. Radiographs revealed a well‐defined expansile lytic bone and soft tissue mass obliterating metacarpal I with smooth ...
Lauren Ho, Jamie‐Leigh Thompson
wiley   +1 more source

Treated Primary Cutaneous Malignant Melanoma With Later Metastasis Found in Clinical Presentation of Left Axilla Lymphadenopathy: A Case Report. [PDF]

Cureus
Cochran BL, Eliseo S, Vaughn A, Van Der Horn TL, Ferrara E, Edwards J.   +5 more
europepmc   +1 more source