Results 61 to 70 of about 68,932 (348)

Liquid Biopsy Utility for the Surveillance of Cutaneous Malignant Melanoma Patients

Molecular Oncology, 2015
Cutaneous melanoma is one of the highest incident‐rate cancers with increasing prevalence in Western societies. Despite the advent of new approved therapeutics, the 5‐year overall survival rate of stage IV melanoma patients remains below 15%.
S. Huang, Dave S.B. Hoon
semanticscholar   +1 more source

Caffeine Intake, Coffee Consumption, and Risk of Cutaneous Malignant Melanoma

Epidemiology, 2015
Background: Caffeine has been shown to prevent ultraviolet radiation-induced carcinogenesis and to inhibit growth of melanoma cells in experimental studies.
Shaowei Wu, Jiali Han, F. Song, E. Cho, Xiang Gao, D. Hunter, A. Qureshi   +6 more
semanticscholar   +1 more source

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis [PDF]

, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Graf, M, Mesher, D, Francesca Moretti, Chiorino, G, A. Chikh, Costanzo, A, M. Graf, D. Bergamaschi, Leigh, IM, Cerio, R, Maria Scatolini, Chong, SLP, C. M. Proby, Anissa Chikh, Antonio Costanzo, Matin, RN, Moretti, F, COSTANZO, ANTONIO, Charlotte M. Proby, Valentina Senatore, C. A. Harwood, Senatore, V, I. M. Leigh, D. Mesher, Harwood, CA, Catherine A. Harwood, R. N. Matin, Stephanie Law Pak Chong, Paolo Sanza’, Rino Cerio, R. Cerio, Bergamaschi, D, David Mesher, P. Sanza', M. Scatolini, Irene M. Leigh, S. L. Pak, Rubeta N. Matin, Proby, CM, V. Senatore, Daniele Bergamaschi, F. Moretti, Chikh, A, Sanza', P, Scatolini, M, Giovanna Chiorino, G. Chiorino, Manuela Graf   +47 more
core   +1 more source

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source

A rare case of melanoma erysipeloides

Clinical Case Reports, 2022
Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report a case of inflammatory metastasis of cutaneous melanoma (CM).
Mariem Rekik, Chaima Kouki, Nadine kammoun, khadija Sellami, Mariem Triki, Sonia Boudaya, Emna Bahloul, Mariem Amouri, Tahya Boudawara, Hamida Turki   +9 more
doaj   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

Overexpression of CDCA8 promotes the malignant progression of cutaneous melanoma and leads to poor prognosis

International Journal of Molecular Medicine, 2018
Cutaneous melanoma is very aggressive and results in high mortality rates for cancer patients. Determining molecular targets is important for developing novel therapies for cutaneous melanoma.
Chao Ci, Biao Tang, D. Lyu, Wen-bei Liu, D. Qiang, Xiang-Bo Ji, X. Qiu, Lei Chen, W. Ding   +8 more
semanticscholar   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Melanoma with gastric metastases [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
An 81-year-old woman with a history of malignant melanoma who presented with dyspnea and fatigue was found to have metastases to the stomach detected on endoscopy.
Katherine Wong, Sam W. Serafi, Abhijit S. Bhatia, Irene Ibarra, Elizabeth A. Allen   +4 more
doaj   +1 more source

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

Head &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder, L. J. van de Velde, T. de Bie, R. van Noortwijk, C. P. J. Raaijmakers, E. H. Voormolen, W. W. Braunius, R. de Bree, G. E. Breimer, L. A. Devriese, E. J. Smid, J. A. Rijken   +11 more
wiley   +1 more source