Results 121 to 130 of about 134,257 (306)

Giant melanoma of the abdomen: case report and revision of the published cases. [PDF]

, 2014
Malignant melanoma presenting as a giant cutaneous mass is rarely observed in clinical practice. A few patients with giant melanoma have been reported, Herein, we document our experience with a patient with giant cutaneous melanoma of the abdomen and ...
Albano, A, Bonin, S, di Meo, N, Errichetti, E, Gatti, A, Stinco, Giuseppe, Trevisan, G., Trevisini, S   +7 more
core  

Performance of a Deep Learning Algorithm for Melanoma Classification Across Diverse Dermoscopic and Tele‐Dermatology Datasets

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Early detection of melanoma significantly boosts patient survival rates. Deep learning has demonstrated dermatologist‐level accuracy in assessing pigmented skin lesions by analysing images at the pixel level. However, these neural networks may face challenges with ‘real‐life’ images due to limited training data and image artefacts ...
Marianne Zanchetta, Fanny Gohard, Casandra Coltoiu, Sarah Le Naour, Marie Le Moigne, Valérie Pham‐Huu, Nicole Cochelin, Edmond Demoulins, Bryan Boule, Thibault Maho, Léonie Schroder, Nicolas Diris, Gaëlle Quereux, Brigitte Dreno, Lise Boussemart, Javier Saenz   +15 more
wiley   +1 more source

A Case of Pembrolizumab‐Induced Pityriasis Lichenoides‐Like Eruption Treated Successfully With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune‐checkpoint inhibitors (ICIs) have revolutionised melanoma treatment but can often cause severe and long‐standing cutaneous immune‐related adverse events (cirAEs). We report a case of refractory pembrolizumab‐induced pityriasis lichenoides (PL)‐like eruption successfully treated with dupilumab, leading to rapid and sustained remission ...
Evangelos Christou, Sharon Edwards, Andrew Affleck   +2 more
wiley   +1 more source

Loss of testosterone impairs anti-tumor neutrophil function. [PDF]

, 2020
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent ...
Arditi, Moshe, Crother, Timothy R, Lane, Malcolm E, Luu, Michael, Markman, Janet L, Martinon, Daisy, Noval Rivas, Magali, Porritt, Rebecca A, Posadas, Edwin M, Wakita, Daiko   +9 more
core   +1 more source

Granulomatous Panniculitis in a Patient Treated With Cemiplimab: Case Report and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have become a cornerstone in the treatment of advanced malignancies by enhancing antitumor immunity, but they may also trigger a broad spectrum of immune‐related adverse events (irAEs) involving multiple organs.
B. Lada‐Colunga, J. L. Artola‐Igarza, N. Martinez‐Peña, I. Arevalo‐Ortega, J. Rodriguez‐Blandon, G. Cancho‐Galan, R. Izu‐Belloso   +6 more
wiley   +1 more source

Melanoma in Chile: demographics and clinico-pathological features

Frontiers in Oncology
BackgroundMelanoma incidence is rising globally, yet epidemiological data from Latin America remain limited. In low- and middle-income countries, such data are essential for shaping evidence-based public health strategies.
Erica C. Koch Hein, Erica C. Koch Hein, Francisco Villanueva, Maysa Vilbert, Verónica Araya, Álvaro Abarzúa-Araya, Álvaro Abarzúa-Araya, Andrea Antúnez-Lay, Andrea Antúnez-Lay, Consuelo Cárdenas, Consuelo Cárdenas, Juan Camilo Castro, Juan Camilo Castro, Francisco Dominguez, Francisco Dominguez, Katherine Droppelmann, Katherine Droppelmann, Nicolás Droppelmann, Héctor Galindo, Héctor Galindo, Augusto León, Augusto León, Jorge Madrid, Jorge Madrid, Ximena Mimica, Montserrat Molgó, Montserrat Molgó, Sebastián Mondaca, Sebastián Mondaca, Pablo H. Montero, Pablo H. Montero, Diego Romero, Pablo Uribe, Pablo Uribe, Miguel A. Villaseca, Miguel A. Villaseca, Eugenio Vinés, Eugenio Vinés, Celeste Richardson, Cristian Navarrete-Dechent, Cristian Navarrete-Dechent, Cristian Navarrete-Dechent   +41 more
doaj   +1 more source

Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial

OncoImmunology, 2018
Vitiligo development in melanoma patients during immunotherapy is a favorable prognostic sign and indicates breakage of tolerance against melanocytic/melanoma antigens.
Hansje-Eva Teulings, Esther P. M. Tjin, Karina J. Willemsen, Stephanie van der Kleij, Sylvia ter Meulen, E. Helen Kemp, Gabrielle Krebbers, Carel J. M. van Noesel, Cornelis L. M. C. Franken, Jan W. Drijfhout, Cornelis J. M. Melief, Ludmila Nieuweboer-Krobotova, Omgo E. Nieweg, Jos A. van der Hage, J. P. Wietze van der Veen, Germaine N. Relyveld, Rosalie M. Luiten   +16 more
doaj   +1 more source

Cutaneous melanoma [PDF]

British Journal of Cancer, 2001
Négrier, S, Fervers, B, Bailly, C, Beckendorf, V, Cupissol, D, Doré, J F, Dorval, T, Garbay, J R, Vilmer, C   +8 more
openaire   +2 more sources

Prospects for non-immunological molecular therapeutics in melanoma [PDF]

, 2010
In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies,
Crown, John, Eustace, Alexander J., Mahgoub, Thamir, O'Donovan, Norma, Tryfonopoulos, Dimitrios   +4 more
core  

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

JEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek, Iris Zalaudek, Karolina Zarańska, Bożena Cybulska‐Stopa   +3 more
wiley   +1 more source