Results 221 to 230 of about 134,257 (306)

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors. [PDF]

Int J Mol Sci
Papaccio F, Kovacs D, Marrapodi R, Caputo S, Migliano E, Melucci E, Scalera S, Cota C, Maugeri-Saccà M, Bellei B.   +9 more
europepmc   +1 more source

Occupational disease “Skin cancer caused by UV radiation” – unambiguous facts, heterogeneous consequences

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Werner Aberer, Rainer Hofmann‐Wellenhof, Norbert Sepp, Barbara Ebner, Swen‐Malte John   +4 more
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Reconstruction of large scalp and forehead defects using transposition flaps and guitar‐string sutures. a single‐center retrospective study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Pedro Redondo
wiley   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Prognostic Value of a Novel Nuclear Grading of Cutaneous Melanoma: The UNC Chapel Hill Method. [PDF]

Am J Surg Pathol
McAlpine SG, Srivatsa S, Jones PC, Davari D, Lei V, Melendez-Gonzalez M, Conlon K, Gebrekidan M, Moschos SJ, Collichio FA, Sorah J, Edmiston SN, Conway K, Miedema J, Ollila DW, Thomas NE, Googe PB.   +16 more
europepmc   +1 more source

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, EarlyView.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

Adverse prognosis of GM-CSF expression in human cutaneous melanoma. [PDF]

Neoplasia
García-Martínez E, Nieto-Valle A, Barrio-Alonso C, López-Navarro B, Avilés-Izquierdo JA, Parra-Blanco V, Gutiérrez-Seijo A, Sánchez-Mateos P, Samaniego R.   +8 more
europepmc   +1 more source