Results 181 to 190 of about 82,061 (304)

Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel, Sabrina Bänsch, Laura Adam, Nathan Fekade, Alessandra Rünger, Tim Zell, Daniel J. Smit, Julian Kött, Isabel Heidrich, Michael Weichenthal, Selma Ugurel, Ulrike Leiter, Peter Mohr, Alexandra Geusau, Stephan Grabbe, Markus V. Heppt, Ralf Gutzmer, Jochen Utikal, Jan‐Christoph Simon, Sebastian Haferkamp, Laura Susok, Bastian Schilling, Edgar Dippel, Imke von Wasielewski, Jessica C. Hassel, Carola Berking, Stefan W. Schneider, Christoffer Gebhardt   +27 more
wiley   +1 more source

Cutaneous Squamous Cell Carcinoma in Immunocompromised Patients. [PDF]

Cancers (Basel)
Hwang SH, St John M.
europepmc   +1 more source

Treatment of advanced cutaneous squamous cell carcinoma with cemiplimab in elderly multimorbid patients – a case series

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Patryk Porebski, Katharina Amschler, Michael P. Schön, Kai‐Martin Thoms   +3 more
wiley   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Identification of Basement Membrane-Related Biomarkers in the Progression of Cutaneous Squamous Cell Carcinoma. [PDF]

Int J Mol Sci
Zou S, Huang S, Liu J, Yao R, Yang X, Zhao H, Du L, Wang L, Zhu Y.   +8 more
europepmc   +1 more source

Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller   +7 more
wiley   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Risk of Malignant Transformation in Patients With Oral Lichen Planus or Lichenoid Lesions: A Retrospective Study of 323 Patients With a Minimum of 5‐Year Follow‐Up

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objective To estimate the risk for oral squamous cell carcinoma (OSCC) among patients with oral lichen planus (OLP) or lichenoid lesions (OLL) and the possible risk factors. Material and Methods Two hundred thirty‐nine OLP and 84 OLL patients diagnosed between years 1982 and 2017 were followed up to December 2023, diagnosis of an OSCC, or ...
Mari Vehviläinen, Tuomas Selander, Tuula Salo, Maria Siponen   +3 more
wiley   +1 more source

A Real-World Experience of Cemiplimab in Patients with Advanced Cutaneous Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Ravara M, Sani T, D'Alonzo V, Valente M, Cinotti E, Miracco C, Colucci M, Croce V, Carbonari E, Rana R, Massarelli O, Rubino G, Giannarelli D, Cuomo R, Grimaldi L, Rubegni P, Maio M, Di Giacomo AM.   +17 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source