Results 61 to 70 of about 82,061 (304)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Effects of COVID-19 Lockdown on Tumour Burden of Melanoma and Cutaneous Squamous Cell Carcinoma

Acta Dermato-Venereologica, 2021
The aim of this study was to compare tumour burden in patients who underwent surgery for melanoma and cutaneous squamous cell carcinoma during nationwide lockdown in Spain due to COVID-19 (for the period 14 March to 13 June 2020) and during the same ...
Antonio Tejera-Vaquerizo, Sabela Paradela, Agusti Toll, Jorge Santos-Juanes, Ane Jaka, Alba López, Javier Cañueto, Àlvaro Bernal, Isabel Villegas-Romero, Carla Fernández-Pulido, Héctor Perandones, David Moreno-Ramírez, Carolina Domínguez-Mahamud, Rafael Salido-Vallejo, Onofre Sanmartin, Francisco M. Almazán-Fernández, Pedro Rodríguez-Jiménez, José Bañuls, Sebastian Podlipnik, Alejandra Sandoval-Clavijo, Aram Boada, Beatriz García-Bracamonte, Sara Palencia, David Revilla-Nevreda, Enara Reola-Ramírez, María del Carmen Gómez-Mateo, Mario Linares-Barrios, David Jiménez-Gallo, Carlos González-Cruz, Elia Samaniego, María Navedo-de las Heras, Rosa Taberner, Teresa Ródenas-Herranz, Carmen García-Donoso, Susana Puig, Eduardo Nagore   +35 more
doaj   +1 more source

Retrospective, Registry-based, Cohort Investigation of Clinical Outcomes in Patients with Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma in Finland

Acta Dermato-Venereologica, 2022
Most cases of keratinocyte cancer can be treated effectively with surgery. However, survival is reduced in patients with advanced disease. This retrospective cohort study evaluated overall survival of patients with invasive keratinocyte cancers, and high-
Samuli Tuominen, Liisa Ukkola-Vuoti, Pilvi Riihilä, Jaakko S. Knuutila, Veli-Matti Kähäri, Mariann Lassenius, Tuuli Ranki, Katariina Pousar, Lotta Vassilev, Sauli Vuoti, Kalle Mattila   +10 more
doaj   +1 more source

Cutaneous Squamous Cell Carcinoma in Children

SSRN Electronic Journal, 2015
The article objective consists in approaching a rare condition in children, the cutaneous squamous cell carcinoma (cSCC), whose frequency may become higher due to risk factors accumulation. Analyzing the few data furnished trough available scientific literature, centered mainly on adult pathology, there have been outlined required data for the ...
Georgiana-Cristina Ionescu, Zamfir-Radu Ionescu   +1 more
openaire   +2 more sources

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

Case report of a squamous cell carcinoma arising in a vulvar cutaneous horn

Gynecologic Oncology Reports
Background: Cutaneous horns are rare lesions that consist of a proliferation of keratotic material, often representing animal horns. Rarely, they may be associated with underlying squamous cell carcinomas.
Michael Bell, Erin Crane, Robert Tucker Burks   +2 more
doaj   +1 more source

Invasive head and neck cutaneous squamous cell carcinoma: clinical and histopathological characteristics, frequency of local recurrence and metastasis [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: squamous cell carcinoma is the second most common type of skin malignancy and may evolve to regional lymph node and distant metastases. OBJECTIVE: The objective of this study was to evaluate patients with head and neck cutaneous squamous ...
Luiza Vasconcelos, Juliana Carneiro Melo, Hélio Amante Miot, Mariângela Esther Alencar Marques, Luciana Patricia Fernandes Abbade   +4 more
doaj   +1 more source

Striking enhancement at the site of radiation for nivolumab-induced Stevens-Johnson syndrome [PDF]

, 2018
Stevens-Johnson syndrome is a rare adverse cutaneous drug reaction characterized by epidermal detachment of
Al-Omari, Ahmed, Rancour, Elizabeth A., Shah, Kishan M.   +2 more
core  

A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]

, 2005
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Bernier J, Budach W, Colevas AD, Colleoni M, Conti F, De Placido S, Degardin M, Dische S, Dobrowsky W, Gasparini G, Gralla R, Grau C, Haffty BG, Harrison LB, Hehr T, Kies MS, Koch WM, Munker R, Pouillart P, Poulsen MG, Regine WF, Shin DM, Siu LL, Vici P, Vokes EE, Wendt TG   +25 more
core   +1 more source