Results 121 to 130 of about 51,662 (290)

Serum Levels of Angiopoietin-2, but not Angiopoietin-1, are Elevated in Patients with Erythrodermic Cutaneous T-cell Lymphoma

open access: gold, 2014
Makiko Kawaguchi   +9 more
openalex   +2 more sources

Restricted Expression of the Constant Region 1 of T‐Cell Receptor β by Flow Cytometry Facilitates Detection of T‐Cell Neoplasms With High Specificity but Moderate Predictive Value

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives To determine the diagnostic value of disclosing monotypic T‐cell populations by expression analysis of the constant region 1 of T‐cell receptor β (TRBC1) by flow cytometry, for the detection of T‐cell neoplasms, in a routine hematopathology practice setting.
Nilofar Rajabian   +4 more
wiley   +1 more source

ALK Expression in Nerve Sheath Myxoma: A Potential Diagnostic Pitfall

open access: yes
Journal of Cutaneous Pathology, EarlyView.
Daniel Cole   +6 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

open access: yesEquine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan   +3 more
wiley   +1 more source

Silent pressure: Unveiling spinal lymphoma in horses and its parallels to other species

open access: yesEquine Veterinary Education, EarlyView.
Summary Though the nervous system is an uncommon location for lymphoma, the disease should remain a differential diagnosis in some cases of ataxia in equids. Diagnosis of lymphoma can be challenging, although a combination of cytology, histopathology and immunophenotyping can aid in definitive diagnosis and therefore more accurately guide treatment and
H. E. Taylor, D. Luethy
wiley   +1 more source

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

open access: yesEquine Veterinary Education, EarlyView.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot   +4 more
wiley   +1 more source

CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death

open access: yesThe FEBS Journal, EarlyView.
A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner   +17 more
wiley   +1 more source

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