Results 61 to 70 of about 417 (120)

Optical Coherence Tomography Risk Factors for Progression to Late-Stage Age-related Macular Degeneration in the Amish Eye Study

To characterize the prevalence of some critical optical coherence tomography (OCT) biomarkers-including cuticular drusen and acquired vitelliform lesions (AVLs)-and to identify their relative risk for progression to late age-related macular degeneration (
Velaga, Swetha B, Nittala, Muneeswar G, Haines, Jonathan L, Pericak-Vance, Margaret A, Chung, Yu-Chien, Sadda, SriniVas R, Alhelaly, Mai, Stambolian, Dwight, He, Ye   +8 more
core   +1 more source

Phenotype Characteristics of Patients With Age-Related Macular Degeneration Carrying a Rare Variant in the Complement Factor H Gene

, 2017
Importance: Rare variants in the complement factor H (CFH) gene and their association with age-related macular degeneration (AMD) have been described. However, there is limited literature on the phenotypes accompanying these rare variants.
Jong, E.K. de, de Jong, Eiko K, Hoyng, Carel B, Anneke I. den Hollander, Peto, Tunde; id_orcid, Maartje J. Geerlings, den Hollander, Anneke I, Fauser, Sascha, Eveline Kersten, Geerlings, M.J., Peto, T., Hoyng, C.B., Geerlings, Maartje J, Tunde Peto, Kersten, E., Fauser, S., Eiko K. de Jong, Sascha Fauser, Kersten, Eveline, Hollander, A.I. den, Carel B. Hoyng   +20 more
core   +1 more source

Missense variations in the fibulin 5 gene and age-related macular degeneration

, 2004
Background: Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world. The study of a rare mendelian form of macular degeneration implicated fibulin genes in the pathogenesis of more common forms ...
Moore, Paula A., Russell, Stephen R., Stone, Edwin M., Braun, Terry A., Casavant, Thomas L., Sheffield, Val C., Kuehn, Markus H., Lotery, Andrew J., Eastman, Christopher G.   +8 more
core   +1 more source

The "triple-layer sign": an optical coherence tomography signature for the detection of non-exudative macular neovascularization

PurposeTo assess the sensitivity and specificity of the "triple layer sign" (TLS) (retinal pigment epithelium (RPE), neovascular tissue, and Bruch's membrane) on structural optical coherence tomography (OCT) images for the diagnosis of treatment-na &
Sacconi, Riccardo, Fragiotta, Serena, Querques, Giuseppe, Miere, Alexandra, Borrelli, Enrico, Parravano, Mariacristina, Costanzo, Eliana, Bandello, Francesco, Amoroso, Francesca, Capuano, Vittorio, Souied, Eric H   +10 more
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Pedigrees of six cuticular drusen (CD) families in which whole exome sequencing (WES) was performed.

, 2016
Circle and square symbols indicate female and male individuals, respectively. Symbols with slashes indicate deceased individuals. Black and empty symbols indicate affected and unaffected individuals, respectively.
Lambertus P. W. J. van den Heuvel (552358), Maheswara R. Duvvari (552352), Sascha Fauser (144944), Maartje J. Geerlings (2578048), Dineke Westra (2578057), Kornelia Neveling (139796), Anneke I. den Hollander (142854), Nicole T. M. Saksens (552354), Eiko K. de Jong (233708), Tina Schick (627467), Johannes P. H. van de Ven (552356), Carel B. Hoyng (552359), Bjorn Bakker (2578045), Arjen Henkes (734279), Camiel J. F. Boon (2578051), Marisol del Rosario (2578054)   +15 more
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Spatial Distribution of Cuticular Drusen and its Association with Category-Specific Progression Risk in Intermediate AMD

Abstract Objectives To investigate the spatial distribution pattern of cuticular drusen using en face OCT and determine its relationship with 2-year progression of age-related macular degeneration (AMD). Methods This study included 87 eyes from 57 participants with intermediate AMD and cuticular drusen enrolled in the Amish Eye Study ...
SriniVas Sadda, Jianfeng Huang, Muneeswar Nittala, Giulia Corradetti, Yu-Chien Chung, Alberto Quarta, Rouzbeh Abbasgholizadeh, Ceren Soylu, Shinichiro Chujo, Swetha Bindu Velaga   +9 more
openaire   +2 more sources

Cuticular Drusen Associated Photoreceptor and RPE Optical Property Perturbation Revealed by Adaptive Optics Scanning Laser Ophthalmoscopy

Abstract Purpose To characterize microscopic alteration of photoreceptors and RPE surrounding cuticular drusen in age-related macular degeneration (AMD) using multimodal imaging, including high resolution adaptive optics scanning laser ophthalmoscopy (AOSLO).
Wang, Xiaolin, Hoshi, Sujin, Kadomoto, Shin, Liu, Ruixue, Ip, Michael, Sarraf, David, Sadda, Srinivas R, Zhang, Yuhua   +7 more
openaire   +2 more sources

Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen

Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen
application/pdf Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence tomography (SD-OCT).
openaire  

Additional file 1 of Age-related macular degeneration, subretinal drusenoid deposits, and cuticular and calcified drusen in black and hispanic subjects

Supplementary Material ...
Tan, John M., Fei, Yang, Wang, Liang, Otero-Marquez, Oscar, Bhuiyan, Tasin R., Arevalo, J. Fernando, Lema, Gareth M.C., Smith, Roland Theodore   +7 more
openaire   +1 more source

Development of tools within a Graphical User Interface for the automatic longitudinal analysis of Dry Age-related Macular Degeneration

Tese de mestrado integrado, Engenharia Biomédica e Biofísica (Sinais e Imagens Médicas) Universidade de Lisboa, Faculdade de Ciências, 2022Age-related Macular Degeneration (AMD), a progressive neuroretinal degenerative disease, is the leading cause of ...
Brites, Gustavo Sousa
core   +1 more source