Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis [PDF]
Scientific Reports, 2022 Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka +12 more
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Retinal drusen in glomerulonephritis with or without immune deposits suggest systemic complement activation in disease pathogenesis [PDF]
Scientific Reports, 2022 Retinal drusen are characteristic of macular degeneration and complement activation, but also occur in C3, lupus and IgA nephropathy. This cross-sectional observational study compared drusen counts in different forms of glomerulonephritis.
P. Harraka +7 more
doaj +2 more sources
Retinal drusen counts are increased in inflammatory bowel disease, and with longer disease duration, more complications and associated IgA glomerulonephritis [PDF]
Scientific Reports, 2022 Retinal drusen are deposits of inflammatory proteins that are found in macular degeneration and glomerulonephritis and result, in part, from complement activation.
E. Nicklason +8 more
doaj +2 more sources
Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen [PDF]
Case Reports in Ophthalmology, 2015 Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence ...
Atsuko Sato +3 more
doaj +3 more sources
Heritability of retinal drusen in the Copenhagen Twin Cohort Eye Study. [PDF]
Acta Ophthalmol, 2022 AbstractPurposeTo study age‐ and sex‐adjusted heritability of small hard drusen and early age‐related macular degeneration (AMD) in a population‐based twin cohort.MethodsThis was a single‐centre, cross‐sectional, classical twin study with ophthalmic examination including refraction, biometry, best‐corrected visual acuity assessment, colour and ...
Belmouhand M +7 more
europepmc +4 more sources
Retinal drusen: harbingers of age, safe havens for trouble [PDF]
Age and Ageing, 2009 Drusen are small focal extracellular deposits underneath the retina, visible ophthalmoscopically as yellow dots. The more hard drusen there are, the greater the risk of developing soft drusen and retinal pigmentary changes, which in turn increase the risk of developing advanced age-related macular degeneration.
Dawn Craig, Craig D, Silvestri G
exaly +4 more sources
The Epidemiology of Retinal Reticular Drusen [PDF]
American Journal of Ophthalmology, 2008 To describe the prevalence and 15-year cumulative incidence of and risk factors for reticular drusen.Population-based prospective study.Four thousand nine hundred and twenty-six persons, 43 to 86 years of age, were included between 1988 and 1990, of whom 3,684, 2,764, and 2,119 participated in five-, 10-, and 15-year follow-up examinations ...
Sudha Iyengar, Ronald Klein
exaly +3 more sources
Drusen Segmentation From Retinal Images via Supervised Feature Learning
IEEE Access, 2018 This paper presents a supervised feature learning method to learn discriminative and compact descriptors for drusen segmentation from retinal images.
Xiuxiu Ren, Yanna Zhao, Chao Luo
exaly +3 more sources
Large drusen in long-standing retinal detachment
Oman Journal of Ophthalmology, 2018 Drusen are seen as an end result of various biochemical insults to the retina and have been described in various clinical settings. We would like to report the histopathology of a case of large drusen, seen associated with chronic retinal detachment in a
Rajiv Raman +3 more
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Large drusen following long-standing retinal detachment
Indian Journal of Pathology and Microbiology, 2010 We report an interesting finding of multiple large drusen in an eviscerated eye with a longstanding retinal detachment. The origin and composition of the drusen is also speculated on the basis of special stains.
Shenoy Sandhya +2 more
doaj +3 more sources