Results 21 to 30 of about 1,953 (166)

Retinal drusen counts are increased in inflammatory bowel disease, and with longer disease duration, more complications and associated IgA glomerulonephritis

Scientific Reports, 2022
Retinal drusen are deposits of inflammatory proteins that are found in macular degeneration and glomerulonephritis and result, in part, from complement activation.
E. Nicklason, Y. Ham, D. Ng, S. Glance, K. Abel, P. Harraka, H. Mack, D. Colville, J. Savige   +8 more
doaj   +1 more source

Retinal complications of optic disc drusen. [PDF]

British Journal of Ophthalmology, 1982
Following reports by Sanders et al. and Wise et al. of optic disc drusen associated with retinal bleeding, an additional 19 cases were studied and followed up for 1 to 10 years (average 5 years). Four of them showed haemorrhages at the optic disc and its borders only, but 15 showed extensive retinopathy with macular involvement.
K, Rubinstein, M, Ali
openaire   +2 more sources

Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]

, 2012
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger, Yu, Alice L., Burger, Johannes, Welge-Lussen, Ulrich, Alice L Yu, Kerstin Birke, Birke, Kerstin, Alice L. Yu, Ulrich Welge-Lussen   +8 more
core   +1 more source

Retinal findings in membranoproliferative glomerulonephritis

American Journal of Ophthalmology Case Reports, 2017
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed
Ahmad M. Mansour, Luiz H. Lima, J. Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W. Chan   +6 more
doaj   +1 more source

Posterior segment abnormalities in posterior microphthalmos

American Journal of Ophthalmology Case Reports, 2020
Purpose: We report a case of posterior microphthalmos with characteristic papillomacular retinal folds, pigmentary retinopathy, and optic disc drusen.
Nilesh Raval, Cheng Zhang, Wen-Jeng Yao, James Lin   +3 more
doaj   +1 more source

Presumed Bietti crystalline dystrophy with optic nerve head drusen: a case report

Journal of Medical Case Reports, 2022
Background Bietti crystalline dystrophy is primarily a retinal dystrophy caused by a CYP4V2 mutation and typically presents with crystalline retinal deposits in the posterior fundus.
Fatemeh Bazvand, Esmaeil Asadi Khameneh
doaj   +1 more source

Unilateral buried optic nerve head drusen triggering central retinal vein occlusion in young – Discovering an eclipsed entity

Oman Journal of Ophthalmology, 2023
Optic nerve head (ONH) drusen are acellular calcified concretions. Buried drusen manifests as pseudopapilledema. The compressive effects of ONH drusen can rarely precipitate central retinal vein occlusion (CRVO).
Muthu Krishnan Vallinayagam, S Koushik, Amirtha Vaithianathan, Dipika Sainath   +3 more
doaj   +1 more source

Abundant lipid and protein components of drusen. [PDF]

PLoS ONE, 2010
Drusen are extracellular lesions characteristic of aging and age-related maculopathy, a major retinal disease of the elderly. We determined the relative proportions of lipids and proteins in drusen capped with retinal pigment epithelium (RPE) and in RPE ...
Lan Wang, Mark E Clark, David K Crossman, Kyoko Kojima, Jeffrey D Messinger, James A Mobley, Christine A Curcio   +6 more
doaj   +1 more source

Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration

Nature Communications, 2022
Age-related macular degeneration (AMD) is a leading cause of blindness and is characterised by the accumulation of lipid deposits, called drusen. Here, the authors show that mice lacking chloride intracellular channel 4 in retinal pigment epithelium have
Jen-Zen Chuang, Nan Yang, Nobuyuki Nakajima, Wataru Otsu, Cheng Fu, Howard Hua Yang, Maxwell Ping Lee, Armaan Fazal Akbar, Tudor Constantin Badea, Ziqi Guo, Afnan Nuruzzaman, Kuo-Shun Hsu, Joshua L. Dunaief, Ching-Hwa Sung   +13 more
doaj   +1 more source

A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina.

, 2015
Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Lengyel, Imre, Florea, D, Lengyel, I, Csutak, Adrienne, Peto, Tunde, Peto, T, Leung, I, Bird, AC, Florea, Daniela, Csutak, A, Bird, Alan C., Jonasson, Fridbert, Leung, Irene, Jonasson, F   +13 more
core   +1 more source