Results 41 to 50 of about 1,953 (166)

Generation of iPSCs (RFSCi007-A, RFSCi008-A) from a patient with early-onset bilateral drusen and a healthy sibling for retinal disease modeling

open access: yesStem Cell Research
Drusen are extracellular deposits between the retinal pigment epithelium and Bruch’s membrane, commonly linked to age-related macular degeneration (AMD).
Sonali Singh   +8 more
doaj   +1 more source

Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration.

open access: yesPLoS ONE, 2019
Although drusen have long been acknowledged as a primary hallmark of dry age-related macular degeneration (AMD) their role in the disease remains unclear.
Kevin J McHugh   +8 more
doaj   +1 more source

A Case of a Young Asymptomatic Woman with Optic Disc Drusen and Vasculitis

open access: yesCase Reports in Ophthalmology, 2011
Purpose: We present the case of a young woman with optic disc drusen and peripheral vasculitis. Methods: Diagnosis was based on fundoscopic, optical coherence tomography as well as fluorescein angiography (FA) findings.
Tryfon Rotsos   +3 more
doaj   +1 more source

Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber   +3 more
wiley   +1 more source

ACQUIRED VITELLIFORM LESION ASSOCIATED WITH LARGE DRUSEN

open access: yes, 2012
Purpose: the purpose of this study was to describe the association of acquired vitelliform lesion (AVL) and large drusen in patients with non-neovascular age-related macular degeneration.Methods: A retrospective review of clinical examination and ...
Yannuzzi, Lawrence A.   +4 more
core   +1 more source

The impacts of high refractive errors on self‐reported visual function and visual concern

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine the association between refractive errors and self‐reported visual function and visual concern, considering self‐perceived present eyesight, concerns about vision, accomplishing less and limitations in daily activities in an eye‐healthy cohort.
Jens Riis Møller   +9 more
wiley   +1 more source

Drusen-like, sub-RPE deposition, and RPE vacuolization in aged Cxcr5-/- mice.

open access: yes, 2017
Retinal cross sections were prepared from 17-month-old Cxcr5-/- mice (A-D) and C57BL/6 WT control mice (E and F). Cryo-preserved sections were stained with H & E (A, C, and E). Plastic sections were stained with toluidine blue (B, D, and F).
Lei Wang (6656)   +3 more
core   +1 more source

Fluorescence Lifetimes of Drusen in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Purpose The purpose of this study was to characterize fundus autofluorescence lifetimes of retinal drusen in patients with AMD. Methods Patients with AMD and retinal drusen and healthy controls of similar age were examined.
Fink, Rahel   +7 more
core   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen   +5 more
wiley   +1 more source

Laser photocoagulation of soft macular drusen

open access: yesОфтальмохирургия, 2013
Purpose. The assessment of morphological and functional results of the threshold photocoagulation in eyes with large soft macular drusen. Material and methods. Thirty four patients (39 eyes) were enrolled in the study.
L.I. Balashevich   +2 more
doaj  

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