Results 11 to 20 of about 11,800 (170)

Drusen Disappearance After Retinal Detachment Repair

Journal of Vitreoretinal Diseases
Purpose: To describe a case of a drusenoid pigment epithelial detachment that resolved after retinal detachment (RD) repair using multimodal imaging. Methods: A single case was evaluated.
David Wu, Ishrat Ahmed
exaly   +4 more sources

Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors

Journal of Extracellular Vesicles, 2021
Age‐related macular degeneration (AMD) is a leading cause of blindness worldwide. Drusen are key contributors to the etiology of AMD and the ability to modulate drusen biogenesis could lead to therapeutic strategies to slow or halt AMD progression.
S Patricia Becerra, Maria Valeria Canto-Soler, Patrick Mcgrath   +2 more
exaly   +2 more sources

Histologic and Morphometric Comparison of Drusen Associated With Chronic Retinal Detachment and Aging-Associated Drusen. [PDF]

Transl Vis Sci Technol
Drusen are subretinal pigment epithelium extracellular matrix deposits. This study compared histomorphometric characteristics of age-related and atypical drusen found in an eye of a young woman with chronic retinal detachment (RD).We conducted a histomorphometric examination of drusen identified in 3 eyes: an eviscerated eye from a 35-year-old woman ...
Nisanova A, Lin JH, Frauches RL, Estrada M, Nelson AJ.   +4 more
europepmc   +4 more sources

Comet-tailed drusen of the retinal pigment epithelium in angioid streaks [PDF]

Eye, 1998
To describe a fundus finding in angioid streaks, namely comet-tailed drusen of the retinal pigment epithelium.A review was carried out of fundus photographs in 110 cases of angioid streaks.Five patients had comet-tailed drusen and the halo tail was radial and parallel to adjacent angioid streaks.Comet-tailed drusen may represent zones of minor stress ...
Ahmad Mansour, Mansour Ahmad M
exaly   +3 more sources

Retinal Drusen Are More Common and Larger in Systemic Lupus Erythematosus With Renal Impairment [PDF]

Kidney International Reports, 2022
Heather Mack, Judy Savige, David Langsford   +2 more
exaly   +2 more sources

Evaluation of the microperimetry in eyes with cuticular drusen

Scientific Reports, 2022
Retinal sensitivity may vary by subtypes of cuticular drusen. This retrospective study included 52 eyes of 32 patients with cuticular drusen. All the patients underwent assessment of best-corrected visual acuity (BCVA), spectral-domain optical coherence ...
Seung Wan Nam, Jung Hwa Lee, Zeeyoon Byun, Don-Il Ham, Mingui Kong   +4 more
doaj   +1 more source

Cuticular drusen: Age-related macular degeneration in the young - A case report

Indian Journal of Ophthalmology. Case Reports, 2021
A 30-year-old woman presented to the OPD, and during the course of her retinal examination she was seen to have multiple drusen in both the eyes.
Saarang Hansraj, Aliya Sultana, Rajalingam Vairagyam   +2 more
doaj   +1 more source

Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration

EClinicalMedicine, 2020
Background: Epidemiological data show that myeloproliferative neoplasms (MPNs) are associated with increased risk of neovascular age-related macular degeneration (AMD). However, knowledge about the retinal findings in these patients is lacking.
Charlotte Liisborg, Marie Krogh Nielsen, Hans Carl Hasselbalch, Torben Lykke Sørensen   +3 more
doaj   +1 more source

Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model

Nature Communications, 2021
Age-related macular degeneration is characterized by lipid-rich drusen deposits underneath the retinal pigment epithelium (RPE). Here the authors report an in vitro iPSC-RPE model for AMD that recapitulates drusen and RPE atrophy, and identify two drugs ...
Ruchi Sharma, Aman George, Malika Nimmagadda, Davide Ortolan, Barbosa-Sabanero Karla, Zoya Qureshy, Devika Bose, Roba Dejene, Genqing Liang, Qin Wan, Justin Chang, Balendu Shekhar Jha, Omar Memon, Kiyoharu Joshua Miyagishima, Aaron Rising, Madhu Lal, Eric Hanson, Rebecca King, Mercedes Maria Campos, Marc Ferrer, Juan Amaral, David McGaughey, Kapil Bharti   +22 more
doaj   +1 more source

Multimodal Imaging and En Face OCT Detection of Calcified Drusen in Eyes with Age-Related Macular Degeneration

Ophthalmology Science, 2022
Purpose: En face OCT imaging was investigated as a method for the detection and monitoring of calcified drusen in eyes with nonexudative age-related macular degeneration (AMD). Design: Retrospective case series of a prospective study.
Jeremy Liu, BS, Rita Laiginhas, MD, Mengxi Shen, MD, Yingying Shi, MD, Jianqing Li, MD, Omer Trivizki, MD, Nadia K. Waheed, MD, Giovanni Gregori, PhD, Philip J. Rosenfeld, MD, PhD   +8 more
doaj   +1 more source