Results 41 to 50 of about 417 (120)

Exploring the importance of aromatic plants' extrafloral volatiles for pollinator attraction

New Phytologist, Volume 248, Issue 2, Page 517-528, October 2025.
Summary Aromatic plants occur in many plant lineages and have widespread ethnobiological significance. Yet, the ecological significance and evolutionary origins of aromatic volatile emissions remain uncertain. Aromatic emissions have been implicated in defensive interactions but may also have other important functions.
Aphrodite Kantsa, Consuelo M. De Moraes, Theodora Petanidou, Mark C. Mescher   +3 more
wiley   +1 more source

Naphthalene Metabolites From Long‐Term Environmental Tobacco Smoke Induce the Aging of Retinal Pigment Epithelium

Aging Cell, Volume 24, Issue 9, September 2025.
Cigarette exposure can induce the senescence of retinal pigment epithelium (RPE). The accumulation of naphthalene metabolites, namely 1,2‐dihydronaphthalene and 1,2‐naphthoquinone, in rats is a key factor in this process. In ARPE‐19 cells, the plasma of rats exposed to cigarette smoke can cause a significant increase in the level of reactive oxygen ...
Tingting Cui, Qingjian Ou, Zhe Wang, Ye Zhou, Jinyuan Xu, Yifan Liu, Yanlong Bi, Xiaoliang Jin, Jie Chen, Furong Gao, Juan Wang, Jieping Zhang, Lixia Lu, Guo‐Tong Xu, Caixia Jin, Haibin Tian, Jing‐Ying Xu   +16 more
wiley   +1 more source

N‐terminomics and proteomics analysis of Calpain‐2 reveal key proteolytic processing of metabolic and cell adhesion proteins

Protein Science, Volume 34, Issue 5, May 2025.
Abstract Aberrant levels of the cysteine protease Calpain‐2 have been linked to neurodegeneration, inflammation, and cancer, yet our understanding of this protease and its substrates remains limited. Systematic studies to identify Calpain‐2 substrates have been largely confined to peptide libraries or in vitro studies, which fail to represent ...
Anjali Kapilan, Mitchell Bulluss, Alexander R. Ziegler, Mohamed Dabaja, Afshin Derakhshani, Anthonia Anowai, Victoria Armstrong, Rhiannon Campden, Daniel Young, Young Joo Sun, Nichollas E. Scott, Laura E. Edgington‐Mitchell, Vinit B. Mahajan, Antoine Dufour   +13 more
wiley   +1 more source

Natural products targeting tumour angiogenesis

British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu, Lara Johanna Friedrich, Thomas Efferth   +2 more
wiley   +1 more source

Retinal dysfunction in APOE4 knock‐in mouse model of Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Graphical summary of retinal dysfunction in APOE4 knock‐in (KI) mice aged 5257 weeks. The model exhibits vascular deficits (increased vascular tortuosity), behavioral dysfunction (decreased visual acuity and contrast sensitivity), and neuronal deficits (impaired retinal function, bipolar cell stunting, and loss of photoreceptors).
Surabhi D. Abhyankar, Qianyi Luo, Gabriella D. Hartman, Neha Mahajan, Timothy W. Corson, Adrian L. Oblak, Bruce T. Lamb, Ashay D. Bhatwadekar   +7 more
wiley   +1 more source

ACQUIRED VITELLIFORM LESION ASSOCIATED WITH LARGE DRUSEN

, 2012
Purpose: the purpose of this study was to describe the association of acquired vitelliform lesion (AVL) and large drusen in patients with non-neovascular age-related macular degeneration.Methods: A retrospective review of clinical examination and ...
Yannuzzi, Lawrence A., Lima, Luiz H. [UNIFESP], Freund, K. Bailey, Spaide, Richard F., Laud, Ketan   +4 more
core   +1 more source

Update vulval dermatology – diagnostics and therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 1, Page 65-86, January 2025.
Summary The vulva is a periorificial skin area and as such represents a transitional zone with unique functional and physiological characteristics. Knowledge of its anatomy is limited among both the general population and healthcare professionals, and unrealistic expectations of normal proportions are common.
Christine Brägelmann, Linn Wölber, Laura Susok, Waltraud Anemüller, Wiebke Prüßmann, Irina Ivanova, Dennis Niebel   +6 more
wiley   +1 more source

Managing Choroidal Neovascularization in Pseudoxanthoma Elasticum: Outcomes of Vitrectomy and Intravitreal Ranibizumab/Aflibercept Therapy—A Case Report

Case Reports in Ophthalmological Medicine, Volume 2025, Issue 1, 2025.
Background: Pseudoxanthoma elasticum (PXE) is a systemic disorder that affects the skin, eyes, and vascular system. It commonly presents with retinal angioid streaks (ASs) and can lead to vision loss due to subretinal neovascularizations and macular atrophy.
Kazuya Yamashita, Kento Hashizume, Yasumasa Fukuda, Rio Sato, Nobuhiro Ozawa, Hirohisa Kubono, Mari Kawamura, Kotaro Suzuki, Stephen G. Schwartz   +8 more
wiley   +1 more source

Human Retinal Progenitor Cell (hRPC) Migration in Three‐Dimensional (3D) Environments of Varying Stiffness and Composition

Journal of Tissue Engineering and Regenerative Medicine, Volume 2025, Issue 1, 2025.
Retinal degeneration is the leading cause of blindness worldwide. Subretinal implantation of human retinal progenitor cells (hRPCs) has shown great promise in models of retinal degeneration for restoration of vision but is limited by extremely low (< 2%) integration into the retina.
Peng Zhao, Joydip Kundu, Douglas Blanton, Mahboobeh Rezaeeyazdi, Madeleine J. Oudin, Miles A. Miller, Aaron S. Meyer, Sidi A. Bencherif, Petr Y. Baranov, Michael J. Young, Rebecca L. Carrier, Cherie Stabler   +11 more
wiley   +1 more source

Acquired vitelliform detachment in patients with subretinal drusenoid deposits (reticular pseudodrusen) [PDF]

, 2011
PURPOSE: To report a recently observed association of macular vitelliform detachment and subretinal drusenoid deposits (reticular pseudodrusen).
Zweifel, S A, Richard F Spaide, Yannuzzi, L A, Spaide, R F, Sandrine A Zweifel, Lawrence A Yannuzzi   +5 more
core   +1 more source