Results 21 to 30 of about 417 (120)

Exploration of cuticular drusen: comprehensive analysis from multi-modal imaging characteristics to clinical diagnosis and treatment

Yanke Xuebao
With the application of multimodal imaging techniques, a specific subtype of age-related macular degeneration (AMD), known as cuticular drusen, has been identified.
ZHANG Guanghan, ZHANG Xiongze, JI Yuying
doaj   +2 more sources

Association analysis of genetic and environmental risk factors in the cuticular drusen subtype of age-related macular degeneration. [PDF]

Mol Vis, 2012
PURPOSE: To assess the association of gender, cigarette smoking, body-mass index, and nine genetic risk variants with cuticular drusen (CD), a well recognized subtype of age-related macular degeneration (AMD). METHODS: A total of 757 patients with AMD, including 217 patients with CD, and 553 control individuals were interviewed with a questionnaire and
van de Ven JP, Smailhodzic D, Boon CJ, Fauser S, Groenewoud JM, Chong NV, Hoyng CB, Klevering BJ, den Hollander AI.   +8 more
europepmc   +6 more sources

Drusen-specific dark adaptation profiles in intermediate age-related macular degeneration [PDF]

International Journal of Retina and Vitreous
Aims To investigate the influence of macular drusen phenotypes on dark adaptation (DA) in intermediate age-related macular degeneration (iAMD). Methods This cross-sectional, multicentric study enrolled 57 eyes of 43 iAMD patients.
Paolo Forte, Lorenzo Ferro Desideri, Marco Nassisi, Federica Milanesi, Alessandro Feo, Irene Bagnasco, Sharlot M. Iglesia, Giovanni Forte, Davide Scandella, Fabiola Roccatagliata, Vincenzo Fontana, Chiara Maria Eandi, Michele Iester, Jasleen K. Jolly, Martin S. Zinkernagel, Francesco Viola, Massimo Nicolò   +16 more
doaj   +2 more sources

Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen [PDF]

Eye, 2018
To examine the feasibility and utility of dark-adapted two-color fundus-controlled perimetry (FCP) in patients with cuticular, reticular, and soft drusen, and to compare FCP data to microstructural spectral-domain optical coherence tomography (SD-OCT) data.Forty-four eyes (24 eyes of 24 patients with drusen, age 69.4 ± 12.6 years; 20 normal eyes of 16 ...
Pfau, M, Lindner, M, Gliem, M, Steinberg, JS, Thiele, S, Finger, RP, Fleckenstein, M, Holz, FG, Schmitz-Valckenberg, S   +8 more
openaire   +4 more sources

Diagnostic Performance of Ring Aperture Retro Mode Imaging for Detecting Pigment Migration in Age-Related Macular Degeneration [PDF]

Diagnostics
Background/Objectives: Pigment migration is a key biomarker of progression in age-related macular degeneration (AMD). This study assessed the diagnostic performance of ring aperture Retro mode (RAR) imaging for detecting pigment migration and compared ...
Thomas Desmettre, Gerardo Ledesma-Gil, Michel Paques   +2 more
doaj   +2 more sources

Drusen classification and quantification in pseudophakic postmortem eyes implanted with or without blue-light filtering intraocular lenses

The Pan-American Journal of Ophthalmology
Purpose: To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis.
Emmanuel Issa Bassam Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, Miguel N. Burnier   +5 more
doaj   +2 more sources

Multimodal Imaging of Acquired Vitelliform Lesion Diagnosed at Pseudohypopyon Stage [PDF]

Case Reports in Ophthalmological Medicine, 2013
Purpose. To present a case study of a monocular acquired vitelliform lesion, studied with multimodal fundus imaging (spectral-domain-optical coherence tomography, fundus autofluorescence, and fluorescein angiography) with a followup of three years.
Nuno Moreira Gonçalves, Ângela M. Carneiro, Elisete Brandão, Fernando M. Falcão-Reis   +3 more
doaj   +2 more sources

Morphological Changes in the Saw-Tooth Pattern of Cuticular Drusen Associated with Immune Complex-Mediated Membranous Proliferative Glomerulonephritis Type III: A Case Report. [PDF]

Case Rep Ophthalmol
Introduction: Patients with membranoproliferative glomerulonephritis (MPGN) type III may exhibit the saw-tooth pattern of cuticular drusen. This study reports a four-and-a-half-year retrospective time-dependent observation of cuticular drusen associated with immune complex-mediated MPGN type III patients.
Tanaka T, Kase S, Nishiyama-Hirooka K, Saito M, Ishida S.   +4 more
europepmc   +3 more sources

Pathology, multimodal imaging and clinical significance of age-related fundus deposits

Yanke Xuebao
Fundus aging is a key factor and pathological basis for the development and progression of age-related macular degeneration (AMD), which is histopathologically characterized by choroidal capillary atrophy, Bruch’s membrane(BrM) thickening, and ...
CAI Jinyu, JIANG Yanmei, CHEN Ling
doaj   +2 more sources

Drusen characteristics of type 2 macular neovascularization in age-related macular degeneration

BMC Ophthalmology, 2020
Background Type 2 macular neovascularization (MNV) is supposed to be a rare condition in age-related macular degeneration (AMD). The main purpose of this study was to assess accompanying factors of type 2 MNV in AMD.
Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei   +5 more
doaj   +1 more source