Results 21 to 30 of about 64,436 (298)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A New Method for the Real-Time Monitoring of PDC Bit Cutter Wear Based on the Drilling Rate Mode

open access: yesShiyou jixie, 2020
In order to carry out real-time quantitative monitoring on the wear degree of PDC bit cutter, the drilling rate equation suitable for PDC bit was optimized.
Hao Yalong   +5 more
doaj  

THE INCREASE IN DRILLING DURABILITY OF TRICONE BITS

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2018
The process of location error the bit in the chuck was verified experimentally and put into production by measuring the gap between the working surface of the limiting ring and the calibrating surface of the cutter to improve the accuracy of the bit ...
M. Ya. Habibullin   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Method for real-time prediction of cutter wear during shield tunnelling: A new wear rate index and MCNN-GRU

open access: yesMethodsX, 2023
Cutter wear is one of the key factors influencing construction efficiency during shield tunnelling. Prediction of cutter wear can improve construction efficiency by reducing the times of cutter inspections in engineering practice.
Nan Zhang, Lin-Shuang Zhao
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Cutter-Gray_PBD_simulation_output

open access: yes, 2016
This data matrix includes mean species richness values from 50 replicate runs of the R speciation simulation package protractedbirthdeath::summaryrepsim().
Asher D. Cutter (550635)   +3 more
core   +1 more source

Nonhuman Complexity Poetics: Leaf-Cutter Ants and Multispecies Composition

open access: yes, 2022
In this article I examine leaf-cutter ants, and particularly their nest architecture, in terms of what I call an ‘ethological poetics.’ I propose that thinking about leaf-cutter architecture is an engagement with a radically alternative aesthetics.
Cooke, Stuart
core   +1 more source

A Method for Evaluating the Rock Breaking Efficiency of Cutters and Optimizing the PDC Cutter Profile—A Study of Igneous Rock Formations in Shunbei Oilfield

open access: yesEnergies, 2022
The Permian igneous rock in Shunbei Oilfield exhibits high rock strength, which results in a low rate of penetration (ROP) and shortens the cutter’s service life. It is necessary to analyze and evaluate the rock breaking effect of cutters.
Zhuoxin Dong   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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