Results 31 to 40 of about 64,436 (298)

Numerical simulation of cooperative breaking rock by multi-cutter and research on the layout law of disc cutter on cutterhead

open access: yesMeitan kexue jishu, 2023
The cutterhead was one of the key parts of the Tunneling Boring Machine to achieve tunnel mining. Cutterhead’s continuous breaking rock was the rock destruction process under the cutter group.
Yadi LIU   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Field Application of Outer Hanging Subsea Casing Cutting and Retrieving Tool for Deepwater Well Abandonment

open access: yesShiyou jixie, 2018
For the offshore well with a water depth of less than 800 m, the subsea wellhead system must be cut and recovered approximately 4 m under the mud line when the well is permanently abandoned, which is a key part of the permanent well abandonment operation.
Sun Zigang   +4 more
doaj  

DETAILS’ REPAIR OF CONSTRUCTION AND ROAD MACHINES: FLUCTUATIONS’ MODELLING

open access: yesВестник СибАДИ, 2019
Introduction. Hole details are quite widely used in structures of construction and road machines. The specialists apply boring for draft, semi-fair, and in some cases for fair processing of such surfaces.
V. E. Ovsyannikov, V. I. Vasilyev
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Modifikasi Paper Cutter untuk Kerajinan Chenille Stripes

open access: yesDinamika Kerajinan dan Batik: Majalah Ilmiah, 2012
AbstrakSalah satu tahapan dalam pembuatan kerajinan chenille strips adalah memotong lapisan kain menggunakan cutter khusus. Cutter khusus kerajinan chenille strips tidak diproduksi di Indonesia.
Kuncup Putih Kusumadhata
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Influence of Cutting Angle on Temperature Distribution of Cutter

open access: yesShiyou jixie, 2021
The failure of cutter is closely related to cutting temperature, and the formation of cuttings has an impact on the performance and life of cutter. This article builds a rock-breaking mechanics model to conduct numerical simulation analysis on rock ...
Zhang Zaixing   +4 more
doaj  

Study on design of taper shaped skiving cutters for internal gears (Taper shaped cutter ground with trapezoidal wheels used for pinion cutter grinding)

open access: yesNihon Kikai Gakkai ronbunshu, 2017
Taper shaped skiving cutters are commonly used in gear skiving because they provide clearance angles under a simple gear arrangement and they could have lower cutting resistance than cylindrical skiving cutters. Their tooth flanks are generally ground by
Koichiro URIU   +6 more
doaj   +1 more source

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