Results 31 to 40 of about 243,051 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Numerical simulation of cooperative breaking rock by multi-cutter and research on the layout law of disc cutter on cutterhead

open access: yesMeitan kexue jishu, 2023
The cutterhead was one of the key parts of the Tunneling Boring Machine to achieve tunnel mining. Cutterhead’s continuous breaking rock was the rock destruction process under the cutter group.
Yadi LIU   +4 more
doaj   +1 more source

Precision glasscutter [PDF]

open access: yes, 1974
Glass is positioned against preset stops; and glasscutter, which is permanently mounted in carrier support by cutter guide rails, is used to scribe glass at predetermined length.
Coombs, D. S.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Line cutter Patent [PDF]

open access: yes, 1967
Piston in bore cutter for severing parachute control lines and sealing cable hole to prevent water leakage into ...
Chandler, J. A., Grubbs, T. M.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

DETAILS’ REPAIR OF CONSTRUCTION AND ROAD MACHINES: FLUCTUATIONS’ MODELLING

open access: yesВестник СибАДИ, 2019
Introduction. Hole details are quite widely used in structures of construction and road machines. The specialists apply boring for draft, semi-fair, and in some cases for fair processing of such surfaces.
V. E. Ovsyannikov, V. I. Vasilyev
doaj   +1 more source

An Analytical Approach to Cutter Edge Temperature Prediction in Milling and Its Application to Trochoidal Milling

open access: yesApplied Sciences, 2020
Cutter edge temperature in milling is an important factor to cutter life. With high cutting speed and feedrate, the cutting efficiency is high; however, the cutter edge temperature is high, shortening the cutter life.
Qi Deng   +3 more
doaj   +1 more source

Metal shearing energy absorber [PDF]

open access: yes, 1973
A metal shearing energy absorber is described. The absorber is composed of a flat thin strip of metal which is pulled through a slot in a cutter member of a metal, harder than the metal of the strip.
Fay, R. J., Wittrock, E. P.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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