Results 121 to 130 of about 2,352,273 (309)
Advances in Mechanical Engineering, 2016 Cutting force prediction is the key issue for planning and optimising the machining process. To explore the cutting of difficult-to-machine 1Cr13 martensitic stainless steel, an orthogonal test was conducted to study the cutting force and surface ...
Xu Chuangwen +5 more
doaj +1 more source
Dry Forages: Process and techniques (OK-Net EcoFeed Practice Abstract) [PDF]
, 2020 To obtain the best forage quality, cutting at the correct time is important, when cellulose and lignin content is not too high. During spring, cutting early is the best option to preserve forage quality; for grasses, the correct time is beginning of ...
Papi, Eugenio
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
VGG-MFO-orange for sweetness prediction of Linhai mandarin oranges
Scientific ReportsMandarin orange is a popular fruit in China and known worldwide for its unique flavor and nutritional benefits. As consumer demand for fruit quality increases, the fine assessment and grading of fruit sweetness—especially through non-destructive testing ...
Chun Fang +6 more
doaj +1 more source
Health Hazard Manual For Cutting Oils, Coolants, and Metalworking Fluids [PDF]
, 1991 [Excerpt] The metalworker can be exposed to cutting oils during application by two basic routes of entry: skin contact and inhalation. The higher risk jobs tend to be those with high cutting speeds, heavy oil flow, and continuous contact, which may ...
Brown, Nellie J
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 1992 Surface cutting problems in two dimensions are considered for nonrectangular items. An exact solution method is discussed. Outlines of several possible heuristic algorithms are also presented.
Murray, J.
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source