Results 101 to 110 of about 914,536 (301)

Influence of cutting process mechanics on surface integrity and electrochemical behavior of OFHC copper [PDF]

, 2014
The authors gratefully acknowledge the support received from IC ARTS and CEA ValducSuperfinishing machining has a particular impact on cutting mechanics, surface integrity and local electrochemical behavior.
Guillaume Fromentin, FROMENTIN, Guillaume, BESNARD, Rémy, Rémy Besnard, DENGUIR, Lamice, Lamice Denguir, Vincent Vignal, VIGNAL, Vincent, Outeiro, José, MARTINS DO OUTEIRO, Jose Carlos, José Outeiro   +10 more
core   +1 more source

Type two cuts, bad cuts and very bad cut

Journal of Symbolic Logic, 1997
AbstractType two cuts, bad cuts and very bad cuts are introduced in [10] for studying the relationship between Loeb measure and U-topology of a hyperfinite time line in an ω1-saturated nonstandard universe. The questions concerning the existence of those cuts are asked there.
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Machine Learning-Guided Multimodal Synchrotron Analysis Workflow for Fuel Cell Electrocatalyst Discovery

Communications Chemistry
Synchrotron radiation provides exceptional sensitivity and resolution, enabling the acquisition of highly precise information critical for advancing fuel cell technology.
Ankur Baliyan, Sarthak Verma, Kaoru Sasakawa, Masashi Matsumoto, Hideo Inoue, Hideo Daimon, Yoshiharu Sakurai, Yoshiharu Uchimoto, Hideto Imai   +8 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Cutting a pie is not a piece of cake [PDF]

Is there a division among n players of a cake using n-1 parallel vertical cuts, or of a pie using n radial cuts, that is envy-free (each player thinks he or she receives a largest piece and so does not envy another player) and undominated (there is no ...
Stromquist, Walter, Brams, Steven J., Barbanel, Julius B.   +2 more
core  

A new approach of high speed cutting modelling: SPH method [PDF]

, 2006
The purpose of this study is to introduce a new approach of high speed cutting numerical modelling. A lagrangian Smoothed Particle Hydrodynamics (SPH) based model is carried out using the Ls-Dyna software.
J. Limido, Salaün, Michel, J.L. Lacome, Lacome, Jean-Luc, M. Salaun, C. Espinosa, Espinosa, Christine, Limido, Jérôme   +7 more
core   +1 more source

Reassessing the origin of organic compounds in Mariana forearc serpentinite mud volcanoes: insights from isotopologue and molecular signatures

Progress in Earth and Planetary Science
Serpentinization-associated geofluid systems are thought to facilitate the abiotic synthesis of organic compounds, which may have played a key role in the prebiotic chemical evolution on the early Earth.
Koudai Taguchi, Shinsuke Kawagucci, Alexis Gilbert, Yuichiro Ueno, Yohei Matsui, Yoshinori Takano, Eiji Tasumi, Masayuki Miyazaki, Akiko Makabe, Junichi Miyazaki, Hikaru Sawada, Naoto Takahata, Ken Takai   +12 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source