Results 101 to 110 of about 2,352,273 (309)

Reassessing the origin of organic compounds in Mariana forearc serpentinite mud volcanoes: insights from isotopologue and molecular signatures

Progress in Earth and Planetary Science
Serpentinization-associated geofluid systems are thought to facilitate the abiotic synthesis of organic compounds, which may have played a key role in the prebiotic chemical evolution on the early Earth.
Koudai Taguchi, Shinsuke Kawagucci, Alexis Gilbert, Yuichiro Ueno, Yohei Matsui, Yoshinori Takano, Eiji Tasumi, Masayuki Miyazaki, Akiko Makabe, Junichi Miyazaki, Hikaru Sawada, Naoto Takahata, Ken Takai   +12 more
doaj   +1 more source

Cutting carbon, not the economy [PDF]

A drastic change in the way we produce and consume energy is necessary to contain the risk of global environmental catastrophe. For its part, the EU has set agreed to a greenhouse gas reduction target of 80-95 percent by 2050, compared to 1990. However,
Georg Zachmann
core   +1 more source

Investigation of tool geometry effect and penetration strategies on cutting forces during thread milling [PDF]

, 2014
The application of thread milling is increasing in industry because of its inherent advantages over other thread cutting techniques. The objective of this study is to investigate the effect of milling cutter tool geometry on cutting forces during thread ...
BRENDLEN, Romain, FROMENTIN, Guillaume, POULACHON, Gérard, SHARMA, Vishal   +3 more
core   +3 more sources

Cutting convex curves

, 2016
We show that for any two convex curves $C_1$ and $C_2$ in $\mathbb R^d$ parametrized by $[0,1]$ with opposite orientations, there exists a hyperplane $H$ with the following property: For any $t\in [0,1]$ the points $C_1(t)$ and $C_2(t)$ are never in the ...
Holmsen, Andreas F., Kincses, János, Roldán-Pensado, Edgardo   +2 more
core   +1 more source

OBJ CUT

2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05), 2005
In this paper, we present a principled Bayesian method for detecting and segmenting instances of a particular object category within an image, providing a coherent methodology for combining top down and bottom up cues. The work draws together two powerful formulations: pictorial structures (PS) and Markov random fields (MRFs) both of which have ...
Kumar, MP, Torr, PHS, Zisserman, A
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A performance of 2 dimensional ultrasonic vibration assisted milling in cutting force reduction, on aluminium AL6061 [PDF]

, 2016
This paper were investigate a performance of 2 Dimensional Ultrasonic Vibration assisted Milling (UVAM) toward Aluminium Al 6061. The focus is to find the performance of reduction of cutting force compared to the conventional machining in the industries ...
Abd. Rahim, Erween, Hui, Ding, Ibrahim, Rasidi, Kai, Cheng, Rafai, Noor Hakim   +4 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

DEFLECTIONS AND FREQUENCY ANALYSIS IN THE MILLING OF THIN-WALLED PARTS WITH VARIABLE LOW STIFFNESS

Acta Polytechnica, 2019
The disadvantage of the geometry of thin-walled parts, in terms of processing, is the low ability to resist static and dynamic loads. It is caused by the elastic deformation of elements with a low stiffness.
Serhii Kononenko, Sergey Dobrotvorskiy, Yevheniia Basova, Magomediemin Gasanov, Ludmila Dobrovolska   +4 more
doaj   +1 more source