Results 91 to 100 of about 763,744 (316)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

PARTICULARS OF ADSORBENT REGENERATION WITH THE USE OF MICROWAVE ENERGY

Acta Polytechnica, 2019
Energy conservation issues are acute in the world. Compressed air is widely used in the modern industrial production. The production of compressed air is a very energy-intensive process, since most of the energy, which is expended by the compressor ...
Sergey Dobrotvorskiy, Ludmila Dobrovolska, Yevheniia Basova, Borys Aleksenko   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Machine Learning-Guided Multimodal Synchrotron Analysis Workflow for Fuel Cell Electrocatalyst Discovery

Communications Chemistry
Synchrotron radiation provides exceptional sensitivity and resolution, enabling the acquisition of highly precise information critical for advancing fuel cell technology.
Ankur Baliyan, Sarthak Verma, Kaoru Sasakawa, Masashi Matsumoto, Hideo Inoue, Hideo Daimon, Yoshiharu Sakurai, Yoshiharu Uchimoto, Hideto Imai   +8 more
doaj   +1 more source

An investigation on the mechanics of nanometric cutting and the development of its test-bed

, 2003
The mechanics of machining at a very small depth of cut (100 nm or less) is not well understood. The chip formation physics, cutting forces generation, resulting temperatures and the size effects significantly affect the efficiency of the process and ...
Cheng, K, Guo, XJ, Luo, X, Holt, R
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A smoky sunset in the hills behind Narbethong on Smiths Road, from fire resident in the Clear Range and the Top Naas area, 21st January 2003 [picture] /

, 2003
Title from caption list supplied by the photographer, see file NLA04/564.; Inscriptions: Signed by the photographer in pencil on reverse; "25-15"--in pencil on reverse.; Part of the collection: A blood red noon, photography of the Brindabella & southern ...
Cutting, Jeff, 1945-
core  

Effect of process parameters and optimization of CO2 laser cutting of ultra high performance polyethylene [PDF]

, 2010
The aim of this work is to relate the cutting edge quality parameters (responses) namely: upper kerf, lower kerf, ratio of the upper kerf to lower kerf and cut edge roughness to the process parameters considered in this research and to find out the ...
Olabi, Abdul-Ghani, Eltawahni, Hayat, Benyounis, Khaled   +2 more
core   +1 more source

OBJ CUT

2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05), 2005
In this paper, we present a principled Bayesian method for detecting and segmenting instances of a particular object category within an image, providing a coherent methodology for combining top down and bottom up cues. The work draws together two powerful formulations: pictorial structures (PS) and Markov random fields (MRFs) both of which have ...
Kumar, MP, Torr, PHS, Zisserman, A
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source