Results 71 to 80 of about 464,329 (266)
Type two cuts, bad cuts and very bad cut
Journal of Symbolic Logic, 1997 AbstractType two cuts, bad cuts and very bad cuts are introduced in [10] for studying the relationship between Loeb measure and U-topology of a hyperfinite time line in an ω1-saturated nonstandard universe. The questions concerning the existence of those cuts are asked there.
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Communications ChemistrySynchrotron radiation provides exceptional sensitivity and resolution, enabling the acquisition of highly precise information critical for advancing fuel cell technology.
Ankur Baliyan +8 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Progress in Earth and Planetary ScienceSerpentinization-associated geofluid systems are thought to facilitate the abiotic synthesis of organic compounds, which may have played a key role in the prebiotic chemical evolution on the early Earth.
Koudai Taguchi +12 more
doaj +1 more source
DEFLECTIONS AND FREQUENCY ANALYSIS IN THE MILLING OF THIN-WALLED PARTS WITH VARIABLE LOW STIFFNESS
Acta Polytechnica, 2019 The disadvantage of the geometry of thin-walled parts, in terms of processing, is the low ability to resist static and dynamic loads. It is caused by the elastic deformation of elements with a low stiffness.
Serhii Kononenko +4 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source