Results 81 to 90 of about 763,744 (316)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Microtonal Analysis of "Blue Notes" and the Blues Scale

Empirical Musicology Review, 2019
Microtonal evaluation of blue notes in the early blues scale by empirical pitch measurement and statistical characterization has not yet been performed in existing research.
Court B Cutting
doaj   +1 more source

Multi-scale simulation of the nano-metric cutting process

, 2010
Molecular dynamics (MD) simulation and the finite element (FE) method are two popular numerical techniques for the simulation of machining processes. The two methods have their own strengths and limitations.
Cheng, K, Sun, X
core   +1 more source

Effect of CO2 laser cutting process parameters on edge quality and operating cost of AISI316L [PDF]

, 2012
Laser cutting is a popular manufacturing process utilized to cut various types of materials economically. The width of laser cut or kerf, quality of the cut edges and the operating cost are affected by laser power, cutting speed, assist gas pressure ...
T. Inoue, Hagino, M., Olabi, Abdul-Ghani, A.G. Olabi, Eltawahni, Hayat, K.Y. Benyounis, H.A. Eltawahni, Benyounis, Khaled, Inoue, T., M. Hagino   +9 more
core   +1 more source

Cut and Paste

Journal of Computer and System Sciences, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Giansalvatore Mecca, Paolo Atzeni
openaire   +4 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Type two cuts, bad cuts and very bad cut

Journal of Symbolic Logic, 1997
AbstractType two cuts, bad cuts and very bad cuts are introduced in [10] for studying the relationship between Loeb measure and U-topology of a hyperfinite time line in an ω1-saturated nonstandard universe. The questions concerning the existence of those cuts are asked there.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

An investigation on micro cutting mechanics: Modelling, simulations and experimental case studies [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University London.Micro cutting is becoming increasingly important since miniature and micro components/products have become more and more demanded in precision ...
Sawangsri, Worapong
core