Results 81 to 90 of about 914,536 (301)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Estimation the wear state of milling tools using a combined ensemble empirical mode decomposition and support vector machine method

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
Vibrational signals resulting from tool wear have non-linear and non-stationary features. It is also difficult to acquire large numbers of typically worn samples in practice.
Chuangwen XU, Yuzhen CHAI, Huaiyuan LI, Zhicheng SHI   +3 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

A predictive model for the cutting force in wood machining developed using mechanical properties [PDF]

, 2012
In this study a number of work piece variations were evaluated whilst limiting the cutting conditions. Eight wood species controlled at four moisture levels were machined along and across the wood grain.
Andrew Naylor,, Perera, Noel, Emil Clahr, Noel Perera,, Naylor, Andrew, Hackney, Philip, Phil Hackney,, Clahr, Emil   +7 more
core   +1 more source

Modelling flan wear of carbide tool insert in metal cutting [PDF]

, 2005
In this paper theoretical and experimental studies are carried out to investigate the intrinsic relationship between tool flank wear and operational conditions in metal cutting processes using carbide cutting inserts.Anewflank wear rate model, which ...
Liu, X, Luo, X., Holta, R., Cheng, K, Chenga, K., Liu, Xianping, Luo, X, Holt, R   +7 more
core   +1 more source

Cutting parameter-tool material interaction on PcBN tool wear behaviour in ductile iron machining

Scientific Reports
In response to the increasing requirements for the processing quality and precision of ductile iron parts under the trend of automotive lightweighting and emission reduction, this study systematically investigated the wear behavior and cutting parameter ...
Pengfei Wang, Xiaojing Li, Yongtao Jiu, Huiming Yin, Yingbo Zhang   +4 more
doaj   +1 more source

Microtonal Analysis of "Blue Notes" and the Blues Scale

Empirical Musicology Review, 2019
Microtonal evaluation of blue notes in the early blues scale by empirical pitch measurement and statistical characterization has not yet been performed in existing research.
Court B Cutting
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

An Innovative Experimental Study of Corner Radius Effect on Cutting Forces [PDF]

, 2014
The cutting forces are often modelled using edge discretisation methodology. In finish turning, due to the smaller corner radii, the use of a local cutting force model identified from orthogonal cutting tests poses a significant challenge. In this paper,
BISSEY BRETON, Stéphanie, CAMPOCASSO, Sébastien, POULACHON, Gerard, COSTES, Jean-Philippe, Bissey-Breton, Stéphanie   +4 more
core   +1 more source

Cut and Paste

Journal of Computer and System Sciences, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Giansalvatore Mecca, Paolo Atzeni
openaire   +5 more sources