Results 111 to 120 of about 918,916 (305)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Software Control of Machines Based on Typification of Transient Zone Parameters for Processing of Original Non-Circular Parts

Механика машин, механизмов и материалов
The paper provides an overview of trends in the preparation of control programs for CNC metal cutting machines. The direction in the development of programming of machining parts based on the transient zone parameter typification is described.
Nikolay N. Popok, Nikolay V. Belyakov, Stanislav K. Seleznev   +2 more
doaj   +1 more source

A Finite Element Modeling of Orthogonal Cutting

Engineering review (Technical Faculty University of Rijeka), 1997
A finite element model of orthogonal metal cutting is described. The proposed model is based on an updated Lagrangian formulation for plane strain conditions and employs an elastic-plastic material model.
openaire   +1 more source

Boundary element method in evaporative laser cutting

Applied Mathematical Modelling, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kim, Meung Jung, Majumdar, Pradip
openaire   +2 more sources

Blade cutting simulation with crack propagation through thin-walled structures via solid-shell finite elements in explicit dynamics [PDF]

, 2015
To simulate the crack propagation due to blade cutting of a thin-walled shell structure, we propose a numerical technique based on solid shell finite elements and explicit time integration.
Confalonieri, Federica, Ghisi, ALDO FRANCESCO, Perego, Umberto   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Impacts of elevated CO2 and partial defoliation on mineral element composition in rice

Frontiers in Plant Science
IntroductionThis study explores how elevated CO2 concentration may alter the source-sink dynamics in rice by providing additional carbon for photosynthesis, thereby affecting nutrient absorption and distribution.MethodsA free-air CO2 enrichment ...
Bo Gao, Bo Gao, Bo Gao, Shaowu Hu, Mingyuan Zhou, Liquan Jing, Yunxia Wang, Jianguo Zhu, Xingxing Sun, Kai Wang, Yulong Wang, Lianxin Yang   +11 more
doaj   +1 more source

Bases of variational method for calculating of metal-cutting systems accuracy

MATEC Web of Conferences, 2018
The bases of a variation method to calculate the metal-cutting systems accuracy for the first time are systemically stated in this paper. The main attention is paid to a problem of joint influence of geometrical accuracy of machine tools and cutting ...
Anikeeva Olesya, Ivakhnenko Alexander, Erenkov Oleg   +2 more
doaj   +1 more source

О применении метода сглаженных частиц для моделирования процесса прямоугольного свободного резания [PDF]

, 2012
В работе рассмотрено влияние параметров SPH-решателя на погрешность прогнозирования показателей процесса резания, разработана 2-D модель процесса резания на основе SPH-метода с применением регулярной сетки SPH-элементов.
Голобородько, Л. В., Залога, Вильям Александрович, Криворучко, Д. В., Сторчак, М. Г.   +3 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source