Results 61 to 70 of about 918,916 (305)

Особенности создания физической модели процесса образования элементов стружки при обработке глубоких отверстий [PDF]

, 1952
The physical model of the process of chip elements' formation, when materials are processing by cutting, is offered. On the basis of offered physical model, it is possible to create the general math-ematical model, which describes the process of cutting ...
Маршуба, Вячеслав Павлович
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Ultra-Precision Cutting and Characterization of Reflective Convex Spherical Blazed Grating Elements

Micromachines, 2022
In this work, based on the diffraction principle of reflective blazed grating, the structure size of the convex spherical blazed grating unit is determined, the machining accuracy of the convex spherical blazed grating is formulated, the effects of tool ...
Huang Li, Xiaoqiang Peng, Chaoliang Guan, Hao Hu   +3 more
doaj   +1 more source

Влияние демпфирования режущих пластин из поликристаллов КНБ на стойкость резцов [PDF]

, 2010
Досліджено вплив демпфування ріжучих інструментів з використанням вставок з різних матеріалів. Встановлено, що використання нікеліду титану дозволяє знизити шорсткість обробленої поверхні та підвищити стійкість різця.Damping capacities of cutting tool ...
Девин, Л. Н., Деркач, Н. Н., Новиков, Н. В., Осадчий, А. А., Сулима, А. Г.   +4 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Crack propagation in thin shells by explicit dynamics solid-shell models [PDF]

, 2013
A computational technique for the simulation of crack propagation due to cutting in thin structures is proposed. The implementation of elastoplastic solid-shell elements in an explicit framework is discussed.
Pagani, Mara, Perego, Umberto
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Hypoplastic particle finite element model for cutting tool-soil interaction simulations: Numerical analysis and experimental validation

Underground Space, 2018
This study presents numerical and experimental models for the analysis of the excavation of soft soils by means of a cutting tool. The computational model is constructed using an Updated Lagrangean (UL) velocity-based Finite Element approach.
Abdiel Ramon Leon Bal, Ulrich Hoppe, Thai Son Dang, Klaus Hackl, Günther Meschke   +4 more
doaj   +1 more source

An in-depth investigation of the cutting speed impact on the degraded microstructure of worn PCBN cutting tools [PDF]

, 2011
The impact of an increased cutting speed on the degradation of a low content polycrystalline cubic boron nitride (PCBN) tool material is investigated by advanced microscopy techniques. The locally affected microstructure of worn PCBN cutting tools, after
Andrén, Hans-Olof, Angseryd, Jenny
core   +1 more source