Results 21 to 30 of about 2,290,071 (246)

A predictive model for the cutting force in wood machining developed using mechanical properties [PDF]

open access: yes, 2012
In this study a number of work piece variations were evaluated whilst limiting the cutting conditions. Eight wood species controlled at four moisture levels were machined along and across the wood grain.
Andrew Naylor,   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Estimates of the bistable region in metal cutting [PDF]

open access: yes, 2008
The classical model of regenerative vibration is investigated with new kinds of nonlinear cutting force characteristics. The standard nonlinear characteristics are subjected to a critical review from the nonlinear dynamics viewpoint based on the ...
Dombovari, Zoltan   +4 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Metal cutting modelling SPH approach [PDF]

open access: yes, 2011
The purpose of this work is to evaluate the use of the smoothed particle hydrodynamics (SPH) method within the framework of high speed cutting modelling. First, a 2D SPH based model is carried out using the LS-DYNA® software.
J. Limido   +11 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Multi-scale simulation of the nano-metric cutting process [PDF]

open access: yes, 2010
Molecular dynamics (MD) simulation and the finite element (FE) method are two popular numerical techniques for the simulation of machining processes. The two methods have their own strengths and limitations.
Cheng, K, Sun, X
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

From large-scale to micro machining: a review of force prediction models [PDF]

open access: yes, 2013
In this paper, a reviewof work performed in the area of force modelling in metal cutting processes is presented. Past and present trends are described and criticised to compare their relevance with current requirements.
FROMENTIN, Guillaume   +4 more
core  

A review of wood machining literature with a special focus on sawing [PDF]

open access: yes, 2013
In this review, fundamental wood machining research is evaluated to determine the general cutting mechanics of simple, orthogonal, and oblique cutting tools. Simple tool force trends and chip formation characteristics are indentified here, along with the
Phil Hackney   +5 more
core   +1 more source

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