Results 41 to 50 of about 1,485,853 (259)

Investigation of the Relationship between Vibration, Cutting Forces and Tool Wear During the Processing of Inconel 718 Super Alloy under Coolant Pressure Jet-Assisted Turning with Variance Analysis

Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2020
In this study, cutter vibrations, wear conditions and cutting forces are observed during jet-assisted turning under coolant pressure conditions. Inconel 718 material is used as a thread.
Orhan GÜNGÖR, Hüseyin Bilal MACİT
doaj   +1 more source

Machinability investigation in turning of high density fiberboard. [PDF]

PLoS ONE, 2018
A series of experiments were conducted to assess the machinability of high density fiberboard using cemented carbide cutting tools. The objective of this work was to investigate the influence of two cutting parameters, spindle speed and feed per turn, on
Zhaolong Zhu, Dietrich Buck, Xiaolei Guo, Mats Ekevad, Pingxiang Cao, Zhenzeng Wu   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Effect of cutting speed and feed in turning hardened stainless steel using coated carbide cutting tool under minimum quantity lubrication using castor oil

Advances in Mechanical Engineering, 2015
Minimum quantity lubrication is a technique to have the advantages that cutting fluids bring yet keeping their use at minimum. For the cutting fluids, inedible vegetable oils are potential for minimum quantity lubrication machining.
Mohamed Handawi Saad Elmunafi, Noordin Mohd Yusof, Denni Kurniawan   +2 more
doaj   +1 more source

Influence of Cutting Fluid Application Frequency in Micromilling Cutting Forces

International Journal of Engineering Materials and Manufacture, 2021
Micromachining allows the production of parts and components on a micro scale with high precision and has become a key process to meet the growing demand for micro parts and micro components. To meet the quality requirements of the generated surfaces and
Deborah De Oliveira, Milla Caroline Gomes, Aline Gonçalves dos Santos, Marcio Bacci Da Silva   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Numerical and analytical modeling of orthogonal cutting : The link between local variables and global contact characteristics [PDF]

, 2011
The response of the tool–chip interface is characterized in the orthogonal cutting process by numerical and analytical means and compared to experimental results. We study the link between local parameters (chip temperature, sliding friction coefficient,
Miguélez Garrido, María Henar, R. Cheriguene, MOLINARI, Alain, CHERIGUENE, Rachid, MIGUELEZ, Henar, A. Molinari, Molinari, A., H. Miguelez   +7 more
core   +1 more source

The analysis of cutting forces for hardened steel milling

Омский научный вестник, 2023
Micro milling is a widely used manufacturing method. The main purpose of this study is to analyze the cutting forces in corrosion-resistant, heat-resistant steel 14Kh17N2.
D. S. Makashin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source