Results 131 to 140 of about 671,707 (305)

A new material model for 2D numerical simulation of serrated chip formation when machining titanium alloy Ti-6Al-4V [PDF]

, 2008
A new material constitutive law is implemented in a 2D finite element model to analyse the chip formation and shear localisation when machining titanium alloys. The numerical simulations use a commercial finite element software (FORGE 2005) able to solve
CALAMAZ, Madalina, COUPARD, Dominique, GIROT, Franck   +2 more
core   +4 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Impact of cutting forces on surface quality in finish face milling of compacted graphite iron with CBN and nitride ceramic tools

Технічна інженерія
The article presents the results of studies to determine the influence of cutting forces on the quality parameters of machined surfaces as a result of finishing face milling of products made of compacted graphite cast iron (CGI) using round cutting ...
S.I. Radkevych
doaj   +1 more source

Some Effects of the Cutting Fluid on Cutting Force

Journal of the Japan Society of Precision Engineering, 1966
各種の組成を有する切削油剤を用いて, 切削油剤の潤滑効果と冷却効果が, 切削抵抗に及ぼす影響を調べた。超硬バイトによる車軸鋼の切削の場合につき, 普通鋼の高温における機械的性質の変化を考慮に入れて考察した。またそれらに関連して, 切削油剤の作用について, 定性的に一般的考察をした。1) 削り速度20m/min～40m/minにおいては, いずれの切削油剤も有効であるが, 中でも, 極圧潤滑性に富むものの方が, 冷却性に富むものより有効である。水だけでも明らかに切削抵抗を軽減する作用はあるが, その変動係数は比較的大きく, 特に, 削り速度20m/minの場合には, 乾切削の場合よりも大きい。2) 削り速度40m/min以上においては, 塩素系添加剤のものは効果を失い, かえって切削抵抗は高くなる ...
Ryozo FURUICHI, Kentaro TAMAMURA
openaire   +2 more sources

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Influence of Cutting Interactions on Cutting Force of a Pick

AASRI Procedia, 2012
Abstract Various mechanical excavators have been used for rock cutting. The cutting drum of an excavation machine normally consists of a large number of cutting picks. Accurate calculation of cutting force on individual picks is important to machine design and control. In rock cutting, cuts between picks can interact with each other.
Sun, Yong, Li, X.S.
openaire   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Modeling and prediction of cutting forces during the turning of red brass (C23000) using ANN and regression analysis

Engineering Science and Technology, an International Journal, 2017
The life of a cutting tool is greatly influenced by the forces acting on it during a cutting operation. A machining operation is a complex process. It is very difficult to develop a comprehensive model involving all the parameters. The present study aims
M. Hanief, M.F. Wani, M.S. Charoo
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

The Impact Of Cutting Tool Materials On Cutting Force

, 2011
{"references": ["D.I. Lalwani, N.K. Mehta, P.K. Jain, \"Experimental investigations of\ncutting parameters influence on cutting forces and surface roughness in\nfinish hard turning of MDN250 steel\", journal of materials processing\ntechnology, vol. 206, pp. 167-179, 2008.", "Y.K. Chou, M.M. Barash, C.J.
Kamely, M. A., Noordin, M. Y.
openaire   +2 more sources