Results 61 to 70 of about 66,719 (305)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Технічна інженеріяThis article presents the results of an experimental study of cutting forces during face finishing of high-strength spheroidal graphite cast iron EN-GJS-600-3 using a Sandvik Coromant R200-051Q22-12H face milling cutter with round carbide inserts ...
S.I. Radkevych, V.M. Ruban
doaj +1 more source
Determination of Optimum Machining Parameters in Machining Rene 41 Superalloy Depending on Cutting Speed [PDF]
E3S Web of ConferencesRene 41 superalloy developed to withstand severe mechanical stresses and high temperature operation, and are widely used in aircraft and space vehicles, especially nickel-based ones, due to their high corrosion resistance.
Altin Abdullah +3 more
doaj +1 more source
An expert mill cutter and cutting parameters selection system incorporating a control strategy
, 2008 This paper discusses the selection of tools and cutting parameters in milling operations. To carry out this research, an expert system has been developed based on numerical methods of performance evaluation.
De la Sen, Manuel +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Журнал інженерних наук, 2018 Force modeling in metal cutting is important for various purposes, including thermal analysis, tool life estimation, chatter prediction, and tool condition monitoring.
Bashistakumar M., Pushkal B.
doaj +1 more source
A Cyclic Calibration Method of Milling Force Coefficients Considering Elastic Tool Deformation
Machines, 2023 In metal-cutting technology, milling plays an important role in the product development cycle. The accurate modeling and prediction of milling forces have always been research hotspots in this field.
Chang Yang, Rong Yu, Shanglei Jiang
doaj +1 more source
Geometrical analysis of thread milling – Part 2:Calculation of uncut chip thickness [PDF]
, 2010 Thread milling offers interesting possibilities for machining internal or external threads. This machining technique uses a mill with a triangular profile for metric threads and a helical interpolation strategy.
FROMENTIN, Guillaume, POULACHON, Gerard
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Analysis of Indirect Measurement of Cutting Forces Turning Metal Cylindrical Shells [PDF]
, 2014 Cutting forces measurement is an important component of the ma- chining processes development and control. The use of conventional direct meas- urement systems is often impossible as they interfere in the process’s dynamics.
Kirill Kondratenko +10 more
core +1 more source