Results 141 to 150 of about 1,078,585 (298)

Research on cutting performance of micro-texturing tools for cutting aluminum alloys

open access: yesMechanics & Industry
To address the common issues of high cutting forces, poor surface quality, and chip wrapping in aluminium alloy machining, this study innovatively designed two types of micro-groove textures on the tool surface based on the natural flow direction of ...
Xu Tiantian   +4 more
doaj   +1 more source

Ground Reaction Forces and Temporal Characteristics Define Cutting Performance. [PDF]

open access: yesInt J Exerc Sci, 2021
Welinski ML   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Enhancing cutting performance of cemented carbide rotary burrs through coupled electromagnetic treatments of the burrs

open access: yesManufacturing Review
Rotary burrs made of WC-8Co cemented carbide are widely used in automated filing systems, yet rapid cutting-edge wear significantly limits their performance. For this purpose, coupled electromagnetic treatments were applied to the WC-8Co cemented carbide
Zhang Shiyuan   +5 more
doaj   +1 more source

417 Cutting Performance in Dry Cutting

open access: yesThe Proceedings of Conference of Tokai Branch, 2001
Junichi SHINODA   +2 more
openaire   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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