Results 131 to 140 of about 8,927,481 (300)

417 Cutting Performance in Dry Cutting

The Proceedings of Conference of Tokai Branch, 2001
Junichi SHINODA, Eitoku NAKANISHI, Kiyoshi ISOGIMI   +2 more
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Effects of TiC Addition on Mechanical Behavior and Cutting Performance of Powder Extrusion Printed Cemented Carbides

Metals
This study addresses the limited research on the mechanical behavior and cutting performance of additive manufactured cemented carbides with high TiC content, which has impeded the rapid development of additive manufacturing in carbide cutting tools ...
Bisheng Zhong, Dezhi He, Xin Deng, Peishen Ni   +3 more
doaj   +1 more source

Development of a Cutting Technique Modification Training Program and Evaluation of its Effects on Movement Quality and Cutting Performance in Male Adolescent American Football Players. [PDF]

Sports (Basel), 2023
Thieschäfer L, Klütz J, Weig J, Dos'Santos T, Büsch D.   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Recent Advances in Ultrasonic Vibration-Assisted Machining of Ti-Al Intermetallic Compounds

Journal of Manufacturing and Materials Processing
Ti-Al intermetallic compounds (Ti-Al IMCs) are emerging as lightweight, high-temperature structural materials with considerable application potential. Owing to their low density and high-temperature capability, these materials can improve the thrust-to ...
Zongxia Fu, Xuansheng Zhao, Haichao Sun, Xiaofeng Jia   +3 more
doaj   +1 more source

Research on cutting performance and fatigue life of conical pick in cutting rock process. [PDF]

Sci Prog, 2021
Zeng Q, Wang Z, Lu Z, Wan L, Liu Z, Zhang X.   +5 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Ground Reaction Forces and Temporal Characteristics Define Cutting Performance. [PDF]

Int J Exerc Sci, 2021
Welinski ML, Lee LN, McBroom B, Mufarreh B, Gidley AD.   +4 more
europepmc   +1 more source