Results 111 to 120 of about 8,927,481 (300)

Study on the Performances of Cutting Fluids

Journal of the Japan Society of Precision Engineering, 1958
In this report, various kinds of cutting fluids on the market have been evaluated from the view points of cost per unit metal removal, surface roughness, power consumption, antirusting ability, etc., when such steels as SK5 and S25C were machined. Thus, cutting fluids suitable for the machining operations in factories were selected.
SIRAISI, Kenzi, KAKAZU, Koyu
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effect of process parameters and optimization of CO2 laser cutting of ultra high performance polyethylene [PDF]

, 2010
The aim of this work is to relate the cutting edge quality parameters (responses) namely: upper kerf, lower kerf, ratio of the upper kerf to lower kerf and cut edge roughness to the process parameters considered in this research and to find out the ...
Olabi, Abdul-Ghani, Eltawahni, Hayat, Benyounis, Khaled   +2 more
core   +2 more sources

Influence of Molybdenum Addition on the Structure, Mechanical Properties, and Cutting Performance of AlTiN Coatings

Lubricants
Though AlTiN coating has been intensively studied, there is still a need to develop AlTiN coating to meet the growing demand of industrial machining. One effective way to improve the performance of AlTiN coating is by adding alloying elements.
Tao Yang, Jun Yin, Puyou Ying, Changhong Lin, Ping Zhang, Jianbo Wu, Alexander Kovalev, Min Huang, Tianle Wang, Andrei Y. Grigoriev, Dmitri M. Gutsev, Vladimir Levchenko   +11 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Influence of Multiple Used Implant Drills on Their Cutting Performance and Fracture Resistance. [PDF]

Materials (Basel), 2023
Alevizakos V, Mosch R, von See C.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Process acceptability in turning of titanium alloys based on cutting force sensor monitoring

, 2022
S.241-250Turning tests were carried out on a difficult-to-machine Ti alloy (TiAl6V4) under diverse cutting conditions. The principal objective and scope of this work was the reliable and robust identification of Acceptable / Not Acceptable process ...
Teti, R., Segreto, T., Harzbecker, C., Neugebauer, Reimund   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Preparation and cutting performance study of YSZ-toughened PcBN superhard tools. [PDF]

RSC Adv, 2023
Yue Y, Zhu Y, Li Z.
europepmc   +1 more source