Results 41 to 50 of about 157,983 (260)

Study on the Design and Cutting Performance of a Revolving Cycloid Milling Cutter

open access: yesApplied Sciences, 2019
Problems such as low machining efficiency, severe tool wear and difficulty in safeguarding surface quality always exist in the machining process of titanium alloy with ball-end milling cutters.
Guangyue Wang   +4 more
doaj   +1 more source

Cutting performance and tool wear in laser-assisted grinding of SiCf/SiC ceramic matrix composites

open access: yesMaterials Research Express, 2022
Ceramic matrix composites have high hardness, so their machining requires high grinding forces that cause severe wear of the grinding head. To investigate this problem, the present study investigated the cutting performance of conventional grinding (CG ...
Xianjun Kong   +5 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin   +6 more
wiley   +1 more source

Influence of Chip Breaker Geometric Shape on the Cutting Performance of Cermet Tools

open access: yesEng
Ti(C,N)-based cermet turning inserts with two distinct chip breaker groove structures were employed to investigate the influence of chip breaker geometry on cutting performance.
Shuwen Yu   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The Coupled Influence of Material and Geometric Parameters on Cutting-Edge Micro-Morphology and Wear Property Degradation

open access: yesMetals
Cutting-edge wear is inevitable in the cutting process of the knife. Studying the relationship between the performance of the knife and the cutting-edge wear is conducive to optimizing the design of the knife and increasing its service life.
Zhimin Peng   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Performance of TiAlSiN Coated Cemented Carbide Tools Enhanced by Inserting Ti Interlayers

open access: yesMetals, 2019
To enhance the cutting performance of TiAlSiN coated cemented carbide tools by inserting Ti interlayers and to explore their mechanism, TiAlSiN/Ti multilayer coatings with different Ti thicknesses, including 0 nm, 25 nm, 50 nm, 100 nm, and 150 nm, were ...
Guodong Li   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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