Results 51 to 60 of about 8,927,481 (300)

Reduce-and-Split Cuts: Improving the Performance of Mixed-Integer Gomory Cuts [PDF]

open access: yesManagement Science, 2005
Mixed-integer Gomory cuts have become an integral part of state-of-the-art software for solving mixed-integer linear programming problems. Therefore, improvements in the performance of these cutting planes can be of great practical value. In this paper, we present a simple and fast heuristic for improving the coefficients on the continuous variables ...
Kent Andersen   +2 more
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Micro milling performance assessment of diamond-like carbon coatings on a micro-end mill [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Institution of Mechanical Engineers.In micro milling, unpredictable tool life and premature tool failures are the major constraints ...
Cheng, K, Wu, T
core   +1 more source

Application of Cryogenic Minimum Quantity Lubrication Technology in Different Machining Processing for Titanium Alloys: A Review

open access: yesLubricants
Titanium alloys face challenges such as high temperatures, high forces, and tool wear during turning, milling, drilling, and grinding operations. Cryogenic minimum quantity lubrication (CMQL) technology, which combines cryogenic cooling with micro ...
Xiangke Tian   +3 more
doaj   +1 more source

Cutting Performance of Microcrystalline, Nanocrystalline and Dual-Layer Composite Diamond Coated Tools in Drilling Carbon Fiber Reinforced Plastics

open access: yesApplied Sciences, 2018
The drilling of carbon fiber reinforced plastics (CFRP) is a significant topic for the aircraft industry. However, CFRP are materials which are difficult to cut due to their unique properties.
Jianguo Zhang   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Analysis of Milling Performance of High-Entropy Alloys with Different Elemental Ratios Subject to the Assistance of Various Ultrasonic Systems

open access: yesApplied Sciences
High-entropy alloys (HEAs) possess multi-element composition and uniform structure, exhibiting superior microstructure and properties compared to traditional alloys. However, the multi-element composition of HEAs results in a complex internal composition
Shen-Yung Lin, Bo-Chun Chen
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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