Results 121 to 130 of about 2,078,237 (349)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Wound Healing on the Cutting Plane of Ankle Bones after Incomplete Revascularization for Chronic Limb-Threatening Ischemia in an Elderly Patient: A Case Report. [PDF]

open access: yesAnn Vasc Dis, 2022
Kikuchi S   +8 more
europepmc   +1 more source

Application of the Wigner distribution to monitoring cutting tool condition [PDF]

open access: yes
This thesis is about the application of the Wigner distribution to cutting tool monitoring and control. After reviewing traditional methods, a new method is proposed.
Zheng, Kougen
core  

Minimodularity and the Perception of Layout. [PDF]

open access: yes, 1988
In natural vision, information overspecifies the relative distances between objects and their layout in three dimensions. Directed perception applies (Cutting, 1986), rather than direct or indirect perception, because any single source of information (or
BRUNO, NICOLA   +3 more
core  

A CUTTING PLANE ALGORITHM FOR MODULARITY MAXIMIZATION PROBLEM [PDF]

open access: yes
Modularity proposed by Newman and Girvan is the most commonly used measure when the nodes of a graph are grouped into communities consisting of tightly connected nodes.
Yamamoto, Yoshitsugu   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A simplified model for determining the cutting plane during thoracoscopic anatomical partial lobectomy of the right lower lobe. [PDF]

open access: yesTransl Lung Cancer Res, 2021
Liu Y   +9 more
europepmc   +1 more source

A comprehensive and robust procedure for obtaining the nofit polygon using Minkowski sums [PDF]

open access: yes, 2005
The nofit polygon is a powerful and effective tool for handling the geometric requirements of solution approaches to irregular cutting and packing problems. Although the concept was first described in 1966, it was not until the early 90s that the general
Song, Xiang, Bennell, Julia A.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A primal analogue of cutting plane algorithms [PDF]

open access: yes, 1999
This paper deals with algorithmic issues related to the design of an augmentation algorithm for general integer programs. It is shown that every phase of a primal method has a natural analogue in cutting plane algorithms. In particular, the role that the
Spille, B.   +3 more
core  

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