Results 131 to 140 of about 191,202 (337)
MR histological correlation: A method for cutting specimens along the imaging plane in animal or ex vivo experiments [PDF]
, 2005 Olivier Rouvière +6 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Reachability cuts for the vehicle routing problem with time windows [PDF]
This paper introduces a class of cuts, called reachability cuts, for the Vehicle Routing Problem with Time Windows (VRPTW). Reachability cuts are closely related to cuts derived from precedence constraints in the Asymmetric Traveling Salesman Problem ...
Lysgaard, Jens
core
Cutting planes for families implying Frankl’s conjecture
Mathematics of Computation, 2019 We find previously unknown families of sets which ensure Frankl's conjecture holds for all families that contain them using an algorithmic framework. The conjecture states that for any nonempty union-closed (UC) family there exists an element of the ground set in at least half the sets of the considered UC family.
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Recovering Dantzig–Wolfe Bounds by Cutting Planes
Operations ResearchLeveraging Dantzig–Wolfe Decomposition in the Original Variable Space for Mixed-Integer Programming Dantzig–Wolfe decomposition has been extensively applied to solve large-scale mixed-integer programs with decomposable structures, leading to exact solution approaches, such as branch and price.
Rui Chen, Oktay Günlük, Andrea Lodi
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Machining of PAM green Y-TZP: Influence of build and in-plane directions on cutting forces and surface topography [PDF]
, 2023 Laurent Spitaels
openalex +1 more source