Results 111 to 120 of about 23,957 (296)
Cutting Planes and the Complexity of the Integer Hull [PDF]
Cutting Planes and the Complexity of the Integer ...
Hartmann, M.
core
Relaxations and Cutting Planes for Linear Programs with Complementarity Constraints [PDF]
We study relaxations for linear programs with complementarity constraints, especially instances whose complementary pairs of variables are not independent.
Linderoth, Jeff +2 more
core +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
We investigate solving semidefinite programs (SDPs) with an interior point method called SDP-CUT, which utilizes weighted analytic centers and cutting plane constraints. SDP-CUT iteratively refines the feasible region to achieve the optimal solution. The
John Machacek, Shafiu Jibrin
doaj +1 more source
Simulation of Drilling Process for Control of Burr Formation
An analytical force model is presented to simulate the cutting force and the chip flow direction in the drilling process. Three dimensional chip flow is interpreted as a piling up of the orthogonal cuttings in the planes containing the cutting velocities
Takashi MATSUMURA, Jürgen LEOPOLD
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
In this study, a visualized microstructure evolution model for the primary shear zone during NiTi smart alloy machining was established by integrating an analytical cutting model with a cellular automaton method.
Jiaqi Wang +9 more
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
In this paper it is considered the modified simplex imbeddings method, which is related to the class of cutting plane methods. The main feature of this method is the convergence estimation, which depends only on the quantity of simplex vertices, that are
A.V. Kolosnitcyn
doaj
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

