Results 51 to 60 of about 96,665 (264)
Effect of cutting speed on the material removal behaviour for sapphire [PDF]
MATEC Web of ConferencesSapphire optical components are widely used in various industrial sectors. However, they are currently not available through efficient and highly accurate ultra-precision cutting.
Liu Dehui +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Analysis of feed speed and cutting speed of Korean and Japanese combines using a high-speed camera
Tropical Agricultural Research, 2015 Cutting performance of 5 row Daedong industry combines cutting knife and 5 row Kuboda combines cutting blade were experimented using paddy straw as the object. Cutting positions were 68 cm left and right from the centre.
M.H. Lee +5 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The effect of cutting speed on residual stresses when orthogonal cutting TC4
EPJ Web of Conferences, 2015 As one of the most important parameters in mental cutting, cutting speed has a significant influence on residual stress. Finite element method and experiment method are used to study the relationship between cutting speed and residual stress when ...
Liu Chaofeng +3 more
doaj +1 more source
Micromachines, 2018 Monostable vibration can eliminate dynamic bifurcation and improve system stability, which is required in many microelectromechanical systems (MEMS) applications, such as microbeam-based and comb-driven resonators.
Lei Li +3 more
doaj +1 more source
Simulation analysis on influencing factors of cutting head load of longitudinal roadheader
Gong-kuang zidonghua, 2020 In view of problem that single influencing factor can not fully reflect cutting head load and its fluctuation variation law in existing research methods of cutting head load characteristics for roadheader, by analyzing instantaneous load of cutting head,
FENG Junling +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Materials Research and TechnologyIn this study, modifying the austenitizing temperature offers a strategically viable way towards creating blocky retained austenite (BRA) with varying sizes and morphologies in nanostructured bainitic steel, in strikingly contrast to the conventional ...
Shichao Fan +5 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source