Influence of deposition pressure on structure and properties of AlCrSiN/Mo self-lubricating coating
To solve the problem that the cutting temperature rises sharply due to the high friction coefficient of AlCrSiN coated tools during dry cutting, which seriously shortens the service life of the tool, the tribological properties of the coating are ...
WANG Chongyang +9 more
doaj +1 more source
FEM STRUCTURAL ANALYSIS OF A LATHE TOOL BY USING CATIA [PDF]
With the aid of the finite element analysis method can be studied problems whose complexity is given by the complicated geometric configuration of the bodies, material inhomogeneities, anisotropy of the materials, composite materials, etc.
Alin NIOAŢĂ, Alin STĂNCIOIU
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Cutting data for automated turning tool selection in industry [PDF]
This thesis is concerned with the determination of cutting parameters (cutting speed, feed rate and depth of cut) in turning operations within an industrial environment.
Lewis, Paul Robert, Lewis, P.R.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Development of Vertical Vibration Model for Micro-Tiller by Smoothed Particle Hydrodynamics Method
A micro-tiller vibrates severely during the rotary tillage process, which may cause operators to develop white finger disease. However, for most vibration models, the acting force between the soil and the rotary cutter roll was simplified to only a ...
Xiaochan Liu +5 more
doaj +1 more source
Tool wear behavior is mainly influenced by cutting parameters for a given tool–workpiece pair and cutting process. Rapid tool wear increases production costs and deteriorates machining quality in manufacturing industries.
Delin Liu, Zhanqiang Liu, Bing Wang
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Investigation of tool geometry effect and penetration strategies on cutting forces during thread milling [PDF]
The application of thread milling is increasing in industry because of its inherent advantages over other thread cutting techniques. The objective of this study is to investigate the effect of milling cutter tool geometry on cutting forces during thread ...
Sharma, Vishal S. +4 more
core

