Results 51 to 60 of about 4,046,739 (289)
CONDITIONS OF REDUCED COST FOR MACHINE-BUILDING PRODUCTS [PDF]
Fiabilitate şi Durabilitate, 2019 The mathematical model for the cost of processing of machine parts was developed and the conditions for its reduction were determined. Analytically established the existence of a minimum of the cost of processing which achieved at high cutting speeds ...
Dmytro NOVIKOV +2 more
doaj
Lubricants, 2022 Tool wear behavior is mainly influenced by cutting parameters for a given tool–workpiece pair and cutting process. Rapid tool wear increases production costs and deteriorates machining quality in manufacturing industries.
Delin Liu, Zhanqiang Liu, Bing Wang
doaj +1 more source
Investigation of tool geometry effect and penetration strategies on cutting forces during thread milling [PDF]
, 2014 The application of thread milling is increasing in industry because of its inherent advantages over other thread cutting techniques. The objective of this study is to investigate the effect of milling cutter tool geometry on cutting forces during thread ...
Sharma, Vishal S. +4 more
core
Numerical and analytical modeling of orthogonal cutting : The link between local variables and global contact characteristics [PDF]
, 2011 The response of the tool–chip interface is characterized in the orthogonal cutting process by numerical and analytical means and compared to experimental results. We study the link between local parameters (chip temperature, sliding friction coefficient,
Miguélez Garrido, María Henar +7 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Dependence of the Cross Section of the Cut Layer on the Specific Cutting Resistance
MATEC Web of Conferences, 2019 This article deals with the study of the effect of cross section of the cut layer of material and its influence on the specific cutting resistance. Measurement and evaluation were carried out using two machined materials, according to the designation W ...
Petrů Jana +4 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Micromachines, 2022 The cutting tool heats up during the cutting of high-performance super alloys and it negatively affects the life of the cutting tool. Improved tool life can enhance both the machinability and sustainability of the cutting process.
Shafahat Ali +2 more
doaj +1 more source
Tool life prediction and management for an integrated tool selection system [PDF]
, 1996 In machining, it is often difficult to select appropriate tools (tool holder and insert), machining parameters (cutting speed, feed rate and depth of cut) and tool replacement times for all tools due to the wide variety of tooling options and the ...
Alamin, Bubakar B.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source