Results 101 to 110 of about 900,172 (360)

Web-based CBR (case-based reasoning) as a tool with the application to tooling selection [PDF]

open access: yes, 2005
Over the past few years, manufacturing companies have had to deal with an increasing demand for feature-rich products at low costs. The pressures exerted on their existing manufacturing processes have lead manufacturers to investigate internet-based ...
Aamodt   +8 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Evaluation of tribo-vibration characteristics of the finishing turning process of heat-resistant structural steel 20MnMoNi5-5 [PDF]

open access: yesE3S Web of Conferences
This article is devoted to determining the rational range of cutting speeds during longitudinal finish turning of heat-resistant steel 20MnMoNi5-5 based on a set of tribological and vibration parameters of the cutting process.
Gvindjiliya Valery   +3 more
doaj   +1 more source

A Novel (Ti,W)C Cermet Cutting Tool with Remarkable Advantages in Both Mechanical Properties and Self-Lubricating Property

open access: green, 2022
Mingdong Yi   +8 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Research Progress of Magnetorheological Elastomers and Their Vibration Control Applications

open access: yesJournal of Harbin University of Science and Technology
The magnetorheological elastomer is a magnetic control intelligent material that is prepared by the micron magnetic particles dispersed to the polymer elastomer ,which not only has the excellent mechanical properties of the particle ...
LIU Qiang   +4 more
doaj   +1 more source

Study on the Engineering Technology of the Structural Design of the Index-able Turning Tool

open access: yesJournal of Harbin University of Science and Technology, 2017
The optimal geometry of the working part of the cutting tool has an important influence on aspects such as high quality parts processing,improvement of production efficiency and the longer tool life in the cutting process.
HE Geng-huang   +4 more
doaj   +1 more source

Animal residues found on tiny Lower Paleolithic tools reveal their use in butchery [PDF]

open access: yes, 2019
Stone tools provide a unique window into the mode of adaptation and cognitive abilities of Lower Paleolithic early humans. The persistently produced large cutting tools (bifaces/handaxes) have long been an appealing focus of research in the ...
Agam, Aviad   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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