Results 81 to 90 of about 6,421,048 (404)

Effect of Ratio of Nitrogen to Hydrogen on Microstructure and Wear Properties of Plasma Nitrided H13 Steel [PDF]

Cailiao Baohu
Aiming at the problem of early fatigue cracks in plasma nitrided H13 steel precision hot forging dies， plasma nitriding process tests were conducted under a nitriding temperature of 520 ℃， a pressure of 250 Pa and different nitrogen to hydrogen ratio ...
GAO Yuxin, WANG Junbo, CHENG Hu
doaj   +1 more source

Materials, properties, manufacturing methods and cutting performance of innovative ceramic cutting tools − a review

Manufacturing Review, 2019
For mechanical machining the quality of cutting-tool materials is one of the most significant issues that need to be addressed. Enhancement of cutting tool performance may be achieved through the use of modern composition ceramic cutting tools This may ...
S. Grigoriev, S. Fedorov, K. Hamdy
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Optimization for preparing Bi1.68Pb0.32Sr1.75Ca1.85Cu2.85O10+y powders by wet ball milling

Materials Research Express, 2022
Superconducting Bi _1.68 Pb _0.32 Sr _1.75 Ca _1.85 Cu _2.85 O _10+ _y (Bi-2223) powders were prepared by a conventional solid-state reaction using hand grinding and wet ball milling.
Yingwei Chen, Ling Shao, Guomeng Zhao, Qijie Liu, Yingqi Huang, Zhenzhong Liu, Liu Zhu, Tianle Wang, Beibei Zheng   +8 more
doaj   +1 more source

New hardenable CERMETS for cutting and forming applications [PDF]

, 2008
The University Carlos III has developed a new metal matrix composite (MMC) constituted by a dispersion of ceramic particles of TiCN in a steel matrix. The matrix can be hardened by heat treatment, leading to a material with high hardness and toughness ...
Gordo Odériz, Elena
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Research on vibration reduction performance of dynamic vibration absorber based on damping characteristic of a new material

Advances in Mechanical Engineering, 2020
The absorbing effect of traditional dynamic vibration absorber (TDVA) is satisfactory only when the natural frequency is close to the excitation frequency.
Weizhi Song, Zhien Liu, Chihua Lu, Yongchao Li, Bin Li   +4 more
doaj   +1 more source

Data validation: a case study for a feed-drive monitoring [PDF]

, 1999
The monitoring of machine-tools implicated in the metal cutting process is the subject of increasing developments because of requests on control, reliability, availability of machine-tools and on work-piece quality.
Desforges, Xavier, Habbadi, Abdallah, Noyes, Daniel   +2 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source