Results 61 to 70 of about 16,254 (262)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cuttings Transport Using Pulsed Drilling Fluid in the Horizontal Section of the Slim-Hole: An Experimental and Numerical Simulation Study

open access: yesEnergies, 2019
Poor transport of cuttings in horizontal sections of small-bore well holes leads to high torque and increases the risk of the drill becoming stuck, reducing its service life and posing a threat to safe operation.
Xiaohua Zhu, Keyu Shen, Bo Li, Yanxin Lv
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Selection of the best method for vegetative propagation of mature Alnus glutinosa (L.) Gaertn. trees resistant to Phytophthora alni

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
Although alder is readily propagated by seeds our objective was to examine the feasibility of propagating mature Alnus glutinosa (L.) trees by vegetative means that could be used to propagate trees resistant to Phytophthora alni.
Kateřina Novotná, Petra Štochlová
doaj   +1 more source

Cut-Scenes

open access: yes, 2015
acceptedVersion
openaire   +2 more sources

Cut Flowers

open access: yesNuncius, 2017
Designations of still life as natura morta, nature morte, naturaleza muerta are based on a gross misunderstanding. We are only beginning to fully understand how masterfully the genre played with the supposed boundaries between the living and dead. It is above all floral still life painting after 1600, in which the intermediate state between life and ...
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Comparison effects of decapitation and disbudding with application of glucose in rooting of Chrysanthemum cuttings

open access: yesActa Agrobotanica, 2013
Cuttings of Chrysanthemum cv. 'Horim Golden' were decapitated and disbudded or intact cuttings were treated with glucose solution. Both treatments were carried out at different times after excision of the cuttings, Removal of buds on the day of cuttings ...
Edward Borowski, Lidia Kozłowska
doaj   +1 more source

Vertex Cuts

open access: yesJournal of Graph Theory, 2014
AbstractGiven a connected graph, in many cases it is possible to construct a structure tree that provides information about the ends of the graph or its connectivity. For example Stallings' theorem on the structure of groups with more than one end can be proved by analyzing the action of the group on a structure tree and Tutte used a structure tree to ...
Dunwoody, M. J., Krön, B.
openaire   +3 more sources

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