Results 81 to 90 of about 260,054 (360)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Efeitos do ácido indolbutírico e da época de coleta no enraizamento de estacas de goiabeira (Psidium guajava L.) Effects of indolebutiric acid and of collection date on the rooting of guava cuttings (Psidium guajava L.)

Scientia Agricola, 1995
Este trabalho foi desenvolvido com o objetivo de verificar o efeito de concentrações de ácido indolbutírico (AIB) e da época de coleta sobre o enraizamento de estacas de goiabeira (Psidium guajava L.), oriundas de plantas produtoras de frutos de polpa ...
M. S. W. Tavares, E. Kersten, F. Siewerdt   +2 more
doaj   +1 more source

Rock drill for recovering samples [PDF]

, 1969
Rotary impact-type rock drill for recovering rock ...
Ford, A. G.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A leaf bud technique for rapid propagation of cassava (Manihot esculenta Crantz)

Scientia Agricola
The slow rate of multiplication is one of the main constraints on the production of cassava (Manihot esculenta Crantz). This work aimed to evaluate the use of leaf buds for rapid propagation of cassava varieties. Leaf buds were excised from three cassava
Reizaluamar de Jesus Neves, Leonardo Silva Souza, Eder Jorge de Oliveira   +2 more
doaj   +1 more source

Arbuscular mycorrhizal fungi and indolebutyric acid alter rooting rate and physiological characteristics of Lantana camara L. (Verbenaceae)?

Hoehnea, 2018
The objective of this study was to evaluate the rooting and some physiological characteristics of Lantana camara L. (Verbenaceae) stakes in different concentrations of indolebutyric acid (IBA) and its association with the arbuscular mycorrhizal fungi ...
Virton Rodrigo Targino de Oliveira, Mônica Danielle Sales da Silva Fernandes, Cynthia Cavalcanti de Albuquerque, Francisco Fábio Mesquita Oliveira   +3 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Testing of pear trees on their own roots in comparison with important used rootstocks under organic farming conditions with special regard to fire blight (E. amylovora) [PDF]

, 2008
Pear trees on their own roots are tested in comparison to grafted trees in growth and yield characteristics and with special regard to the tolerance to diseases, above all fire blight (Erwinia amylovora).
Brunmayer, R., Fischer, G., Kaufmann, C., Osterc, G., Spornberger, A.   +4 more
core  

Pomegranate transplant stress can be ameliorated by rhizophagus intraradices under nursery management [PDF]

, 2018
Arbuscular mycorrhizal fungi (AMF) establish an obligate mutualistic symbiosis with many plant species, increasing the uptake of phosphorous and other low-mobile nutrients by roots.
Bompadre, Maria Josefina, Colombo, Roxana, Fernandez Bidondo, Laura, Godeas, Alicia Margarita, Ocampo, Juan Antonio, Pardo, Alejandro Guillermo, Silvani, Vanesa Analia   +6 more
core   +1 more source

Cut-Scenes

, 2015
acceptedVersion
openaire   +2 more sources