Results 51 to 60 of about 3,043 (128)

The DOAC‐FRAIL Study—Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are prescribed using fixed dosing regimens, despite limited evidence on their pharmacokinetic behavior in nursing home residents. Participants and Setting One hundred nursing home residents are receiving apixaban, rivaroxaban, dabigatran, or edoxaban in multiple long‐term care facilities in the ...
Irme S. Franssen, Melanie J. de Jong, Lars Visseren, Daan Teerds, Dave Hellenbrand, Yvonne Henskens, Henri Spronk, Daisy J. A. Janssen, Dionne C. W. Braeken, Sander M. J. van Kuijk, Kristien Winckers, Fabienne J. H. Magdelijns   +11 more
wiley   +1 more source

Heterodonty in the teeth of the turiasaurian sauropod from Angeac‐Charente (Early Cretaceous, southwestern France): Comparison of anatomical and geometric morphometric approaches

Journal of Anatomy, EarlyView.
Turiasaurian teeth from Angeac‐Charente exhibit five dental morphotypes and reveal clear heterodonty and anteroposterior size gradient. Qualitative comparative anatomy quickly and efficiently identifies morphotypes, while 3D geometric morphometrics combined with machine learning refine ambiguous cases, demonstrating that qualitative and quantitative ...
Clémence Le Gouellec, Ronan Allain, Jean Goedert, Romain Pintore, Jackson Carter, Rafael Royo‐Torres, Dominique Augier, Raphaël Cornette   +7 more
wiley   +1 more source

The Evolution of Portfolio Theory Under Risk & Uncertainty: From Mean–Variance to AI‐Augmented Investing

Journal of Economic Surveys, EarlyView.
ABSTRACT This article summarizes the evolution of portfolio theory from mean–variance optimization to AI‐augmented investment systems. Rather than treating portfolio models as isolated techniques, it organizes the literature as a sequence of responses to different forms of uncertainty: variance, systematic risk, expected‐return estimation error ...
Xuan Feng, Sofia Yang
wiley   +1 more source

Genetic, phenotypic, and ecological differentiation indicate a new cryptic and threatened species in the orchid genus Epidendrum from Alcatrazes Island, southeastern Brazil

Journal of Systematics and Evolution, EarlyView.
Epidendrum insularis occurs on the remote Alcatrazes Island in the southeastern Brazilian coast. The description of this new cryptic species was only possible by the joint use of molecular markers, reproductive experiments, flower morphometry, functional traits, and community analysis.
Beatriz L. Arida, Giovana N. Trotta, Beatriz C. De Marco, Iris D. P. Ribeiro, Raphael da Silva, Thales M. de Lima, Welington L. Sachetti Junior, Vitor de A. Kamimura, Gabriel P. Sabino, Bárbara S. S. Leal, Lívia Garcia, Edlley M. Pessoa, Fabio Pinheiro   +12 more
wiley   +1 more source

Blue boost: Monochromatic blue light and blue‐enriched spectra (RBW) enhance physiology, bioactive compounds, and yield of strawberry in indoor vertical farming

Photochemistry and Photobiology, EarlyView.
Effects of spectral quality and light regime on the physiological, biochemical, and agronomic responses of strawberry plants grown in an indoor aeroponic system. Constant blue and red light and sinusoidal red and red–blue–white (RBW) light regimes differentially modulated photosynthetic performance, stomatal regulation, antioxidant metabolism, carbon ...
Carlos Henrique Pereira Bento, Fabia Barbosa da Silva, Márcio Rosa, Tiago do Prado Paim, Ítalo Moraes Rocha Guedes, Luciana Arantes Dantas, Erika Crispim Resende, Aurélio Rúbio Neto, Lucas de Jesus Silva, Nyah Dias Mazieri, Fabiano Guimarães Silva   +10 more
wiley   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

Evaluating a Modified American Society of Anesthesiologists Physical Status‐Based Sedation Management System for Pancreatobiliary Endoscopy: A Prospective Feasibility Study

DEN Open, Volume 7, Issue 1, April 2027.
A modified ASA‐PS‐based sedation management system is evaluated in a prospective feasibility study of 2,000 patients undergoing pancreatobiliary endoscopy. Patients are stratified by modified ASA‐PS classification and predefined high‐risk criteria, with anesthesiologist assessment determining sedation providers.
Taro Hanaoka, Kosuke Okuwaki, Masafumi Watanabe, Hiromi Matsuda, Kai Adachi, Akihiro Tamaki, Daisuke Ogawa, Mayuko Sakai, Chika Kusano   +8 more
wiley   +1 more source

The Effects of Service‐Energy Consumption and Cultural Industries on Green Growth in China

Asia &the Pacific Policy Studies, Volume 14, Issue 1, January 2027.
ABSTRACT Final consumption expenditure as a percentage of GDP, our aggregate proxy for energy demand, is negatively and significantly associated with Chinaʼs green growth over 2004–2022. The relationship holds across specifications (H1 supported), with a long‐run elasticity of −1.29 under Fully Modified OLS (FMOLS). ICT adoption provides no significant
Hang Wang, Haiyu Wang
wiley   +1 more source

Extreme Thrombocytosis in Patients With Malignancy; Complications, Management and Outcomes

eJHaem, Volume 7, Issue 6, December 2026.
ABSTRACT Introduction Extreme thrombocytosis (EXT; platelet count >1000 × 109/L) is a rare haematological abnormality that may be primary or reactive. Data on its incidence and management in patients with malignancy are limited. We retrospectively evaluated the incidence, management, and complications of EXT in patients with malignancy over a 12‐year ...
Laura McDonald, Heba Hasan, Lorelyn Donato, Lillie Wylde, Rifa Cardoso, Kevin Boyd, Rita Peralta, Sunil Iyengar, Dima El‐Sharkawi   +8 more
wiley   +1 more source

Biomechanical, Structural, and Composition Characterization of the Vertebra‐Disc Interface

JOR SPINE, Volume 9, Issue 4, December 2026.
ABSTRACT Background The spinal endplate region consists of the cartilage endplate (CEP), bony endplate (BEP), and subchondral trabecular bone (STB). Although this region is often involved in vertebral fractures and disrupted with disc degeneration, the biomechanics of these tissues are incompletely understood. The goal of this study was to characterize
Neilesh R. Frings, Harrah R. Newman, Faysal M. Haque, Veronica A. Caruso, Dawn M. Elliott, Elise F. Morgan   +5 more
wiley   +1 more source