Results 91 to 100 of about 354 (118)

Variations in the H/ACA box sequence of viral telomerase RNA of isolates of CVI988 Rispens vaccine

Archives of Virology, 2008
The use of the complete DNA sequence for the Marek's disease virus (MDV) serotype 1 vaccine strain CVI988 Rispens in comparative genomic studies with virulent strains of MDV has revealed the presence of a number of insertions, deletions and single-nucleotide polymorphisms.
Denis Rasschaert, Ginette Dambrine
exaly   +5 more sources

In vitro characterization of the Meq proteins of Marek's disease virus vaccine strain CVI988

Virus Research, 2009
Gallid herpesvirus 2 (GaHV-2), commonly known as Marek's disease virus serotype-1 (MDV-1), causes T cell lymphomas in chickens. Vaccines prepared from the attenuated CVI988/Rispens MDV-1 strain currently offer the best protection. Although attenuated CVI988/Rispens is non-oncogenic, it codes for at least two forms of the MDV oncoprotein Meq, and these ...
Sanjay Reddy, Blanca Lupiani, Lucy F Lee   +2 more
exaly   +3 more sources

Expression and intercellular trafficking of the VP22 protein of CVI988/Rispens vaccine strain of Marek’s disease virus

Science in China Series C: Life Sciences, 2007
The viral protein 22 (VP22) in the tegument of Marek's disease virus serotype 1 (MDV-1) plays an important role in cell-to-cell spread and viral propagation. Antiserum against the carboxyl terminus of VP22 was prepared by immunizing mice with recombinant VP22 expressed in E. coli, and used to investigate its expression in chicken embryo fibroblast (CEF)
Aijian Qin, Hongjun Chen, Chen Hongjun   +2 more
exaly   +3 more sources

Molecular Identification of the Marek's Disease Virus Vaccine Strain CVI988 in Vaccinated Chickens

Zoonoses and Public Health, 2002
The study describes three polymerase chain reaction (PCR) systems for the CVI988 vaccine virus: the meq gene, the MDV BamHI‐D/H 132 bp tandem repeat fragment and the MDV‐gB gene. Whereas the PCR product of virulent MDV strains and of the CVI988 virus strain with the meq and the 132 bp primer sets differed for the two templates, the MDV‐gB PCR products ...
I, Davidson, R, Borenshtain, Y, Weisman
exaly   +3 more sources

Comparative 50% protective dose assays (PD50) of Marke's disease virus strain CVI988

Journal of Biological Standardization, 1981
Six 50% protective dose (PD50) assays of cell-associated Marek's disease (MD) virus strain CVI988 were performed in five laboratories. Three strains of chickens and different batches of MDV CVI988 were used. The PD50 of cell-associated MDV CVI988 was found to be about 40 f.f.u.
G F De Boer
exaly   +3 more sources

Detection and Differentiation of CVI988 (Rispens Vaccine) from Other Serotype 1 Marek's Disease Viruses

Avian Diseases, 2014
The serotype 1 Marek's disease virus (MDV) is the causative agent for Marek's disease (MD), a lymphoproliferative disease of chickens of great concern to the poultry industry. CVI988 (Rispens vaccine), an attenuated serotype 1 MDV, is currently the most efficacious commercially available vaccine for preventing MD. However, it is difficult to detect and
Isabel Gimeno, John Dunn, Robert F Silva   +2 more
exaly   +3 more sources

Evaluation of Factors Influencing Efficacy of Vaccine Strain CVI988 Against Marek’s Disease in Meat-Type Chickens

Avian Diseases, 2015
Marek's disease (MD) strain CVI988 is the most-protective commercially available vaccine against very virulent plus (vv+) Marek's disease virus (MDV). However, its use in meat-type chickens has been controversial. While several countries have been using CVI988 for more than 40 yr, others do not authorize its use or it is restricted mainly to layers ...
Isabel Gimeno, Nik Faiz, Aneg L Cortes
exaly   +3 more sources

Effects of Rispens CVI988 vaccination followed by challenge with Marek’s disease viruses of differing virulence on the replication kinetics and shedding of the vaccine and challenge viruses

Veterinary Microbiology, 2016
Vaccination with "imperfect" vaccines that prevent disease but not infection is strongly implicated in the observed increased virulence of Marek's disease virus (MDV) over the past six decades. The current "gold standard" vaccine, Rispens CVI988 (Rispens), has maintained efficacy despite use for five decades, raising the question of whether it too ...
Sithara Ralapanawe, Stephen Walkden-Brown   +1 more
exaly   +3 more sources

Effect of Cryptosporidium baileyi in specific pathogen free chickens vaccinated (CVI988/Rispens) and challenged with HPRS-16 strain of Marek's

Avian Pathology, 2000
This study was performed to examine the effect of Marek's disease virus (MDV) serotype 1 vaccine (CVI988/Rispens) on the pathogenicity of Cryptosporidium baileyi , and to determine whether C. baileyi infection could prevent the development of vaccinal Marek's disease (MD) immunity in specific pathogen free (SPF) chickens. Sixty-eight SPF homozygous B13
G Dambrine
exaly   +3 more sources

Characterization of a very Virulent Marek’s Disease Virus Mutant Expressing the pp38 Protein from the Serotype 1 Vaccine Strain CVI988/Rispens

Virus Genes, 2005
Marek's disease virus (MDV), a highly cell-associated oncogenic chicken herpesvirus, causes Marek's disease in domestic chickens. A unique phosphoprotein of MDV, pp38, has previously been associated with the maintenance of transformation in MDV-induced tumor cell lines.
Sanjay Reddy, Blanca Lupiani, Isabel Gimeno   +2 more
exaly   +3 more sources